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Flow Cytometry (FC/FACS) (Flow cytometric analysis of Human PRDX6 expression on HeLa cells. The cells were treated according to manufacturer's manual (BD Pharmingen'), and then stained with FITC Mouse anti-Human PRDX6. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)

Mouse anti-Human Peroxiredoxin 6 Monoclonal Antibody | anti-PRDX6 antibody

Anti-Peroxiredoxin 6 Antibody (FITC), Mouse Monoclonal

Gene Names
PRDX6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
Peroxiredoxin 6; Monoclonal Antibody; Anti-Peroxiredoxin 6 Antibody (FITC); Mouse Monoclonal; Peroxiredoxin 6/PRDX6 Antibody (FITC); Mouse MAb; peroxiredoxin 6; Anti-1-Cys Antibody; Anti-aiPLA2 Antibody; Anti-AOP2 Antibody; Anti-HEL-S-128m Antibody; Anti-NSGPx Antibody; Anti-p29 Antibody; Anti-PRX Antibody; anti-PRDX6 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
03
Specificity
Human Peroxiredoxin 6/PRDX6
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Concentration
10ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-PRDX6 antibody
Flow Cytometry (FC/FACS/FCM)
Immunogen
Recombinant Human Peroxiredoxin 6/PRDX6 protein
Conjugation
FITC
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Peroxiredoxin 6/PRDX6 (rh Peroxiredoxin 6/PRDX6) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of Human PRDX6 expression on HeLa cells. The cells were treated according to manufacturer's manual (BD Pharmingen'), and then stained with FITC Mouse anti-Human PRDX6. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of Human PRDX6 expression on HeLa cells. The cells were treated according to manufacturer's manual (BD Pharmingen'), and then stained with FITC Mouse anti-Human PRDX6. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)
Related Product Information for anti-PRDX6 antibody
PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase (GPx) and iPLA2 activities, which are concomitantly increased with the expression of PRDX6. PRDX6 promoted lung tumor growth in an in vivo allograft model.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Observed: 27kDa
Calculated: 25kDa
NCBI Official Full Name
Peroxiredoxin-6
NCBI Official Synonym Full Names
peroxiredoxin 6
NCBI Official Symbol
PRDX6
NCBI Official Synonym Symbols
PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
NCBI Protein Information
peroxiredoxin-6; 1-Cys PRX; 24 kDa protein; 1-Cys peroxiredoxin; antioxidant protein 2; liver 2D page spot 40; red blood cells page spot 12; non-selenium glutathione peroxidase; acidic calcium-independent phospholipase A2; epididymis secretory sperm bindi
UniProt Protein Name
Peroxiredoxin-6
Protein Family
UniProt Gene Name
PRDX6
UniProt Synonym Gene Names
AOP2; KIAA0106; 1-Cys PRX; aiPLA2; NSGPx
UniProt Entry Name
PRDX6_HUMAN

NCBI Description

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

Uniprot Description

PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily.

Protein type: Amino Acid Metabolism - phenylalanine; Oxidoreductase; Energy Metabolism - methane; EC 1.11.1.9; EC 1.11.1.15; Phospholipase

Chromosomal Location of Human Ortholog: 1q25.1

Cellular Component: extracellular space; membrane; lysosome; cytoplasmic membrane-bound vesicle; cytoplasm; cytosol

Molecular Function: antioxidant activity; phospholipase A2 activity; protein binding; peroxiredoxin activity; glutathione peroxidase activity

Biological Process: response to reactive oxygen species; phospholipid catabolic process; hydrogen peroxide catabolic process; response to oxidative stress

Research Articles on PRDX6

Similar Products

Product Notes

The PRDX6 prdx6 (Catalog #AAA8105168) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Peroxiredoxin 6 Antibody (FITC), Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Peroxiredoxin 6 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the PRDX6 prdx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peroxiredoxin 6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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