Western Blot (WB)
(Western Blot analysis of lysates prepared from mouse heart (Lane 1) or lymph node cells (Lane 2) using PDE3B antibody (2 ug/ml) followed by Rat IgG HRP antibody.)
Rat PDE3B Monoclonal Antibody | anti-PDE3B antibody
PDE3B antibody
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest.
Western Blot (WB)
(Western Blot analysis of lysates prepared from mouse heart (Lane 1) or lymph node cells (Lane 2) using PDE3B antibody (2 ug/ml) followed by Rat IgG HRP antibody.)
Western Blot (WB)
(Western Blot analysis of lysates prepared from mouse heart (Lane 1) or lymph node cells (Lane 2) using PDE3B antibody (2 ug/ml) followed by Rat IgG HRP antibody.)
NCBI and Uniprot Product Information
Uniprot Description
PDE3B: a cGMP-inhibited phosphodiesterase 1 involved in fat metabolism. Inhibition of PDE3B can augment PDE4 inhibitor-induced apoptosis in some patients with chronic lymphocytic leukemia.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Phosphodiesterase; Nucleotide Metabolism - purine; EC 3.1.4.17
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: Golgi apparatus; membrane; endoplasmic reticulum; integral to membrane; cytosol
Molecular Function: protein kinase B binding; protein binding; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; metal ion binding; 3',5'-cyclic-nucleotide phosphodiesterase activity
Biological Process: negative regulation of angiogenesis; cellular response to insulin stimulus; negative regulation of lipid catabolic process; cAMP catabolic process; insulin receptor signaling pathway; angiogenesis; negative regulation of cell adhesion; blood coagulation; glucose homeostasis; endocrine pancreas development; negative regulation of cell adhesion mediated by integrin; regulation of insulin secretion
Research Articles on PDE3B
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Product Notes
The PDE3B pde3b (Catalog #AAA833563) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PDE3B can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC: <= 1 ug/test A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest. Researchers should empirically determine the suitability of the PDE3B pde3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE3B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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