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ELISA (EIA)

Human anti-Human PD-1 Monoclonal Antibody | anti-PD-1 antibody

Anti-PD-1 (Nivolumab) Biotinylated Antibody

Gene Names
Pdcd1; PD-1; Pdc1; Ly101
Reactivity
Human
Applications
ELISA
Purity
Affinity purified
Synonyms
PD-1; Monoclonal Antibody; Anti-PD-1 (Nivolumab) Biotinylated Antibody; anti-PD-1 antibody
Ordering
For Research Use Only!
Host
Human
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG4
Specificity
Mouse monoclonal antibody to detect biotinylated PD-1 in human samples
Purity/Purification
Affinity purified
Form/Format
Colorless liquid. In PBS; pH7.2; 30% glycerol; 0.5% BSA; 0.5mM EDTA and 0.03% proclin
Applicable Applications for anti-PD-1 antibody
ELISA (EIA)
Application Notes
ELISA: 1ug
Antibody Target
PD-1
Immunogen
Human programmed cell death 1 receptor (PD1)
Preparation and Storage
Store at -20 degree C. The antibody solution should be gently mixed before use.
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA

ELISA (EIA)

ELISA (EIA)
Related Product Information for anti-PD-1 antibody
Nivolumab, trade name Opdivo, is a medication used to treat cancer. It is used as a first line treatment for inoperable or metastatic melanoma in combination with Iplimumab if the cancer does not have a mutation in BRAF, as a second-line treatment following treatment with Iplimumab and if the cancer has a mutation in BRAF, with a BRAF inhibitor, as a second-line treatment for squamous non-small cell lung cancer, and as a second-line treatment for renal cell carcinoma.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
31,842 Da
NCBI Official Full Name
Programmed cell death protein 1
NCBI Official Synonym Full Names
programmed cell death 1
NCBI Official Symbol
Pdcd1
NCBI Official Synonym Symbols
PD-1; Pdc1; Ly101
NCBI Protein Information
programmed cell death protein 1; mPD-1; protein PD-1
UniProt Protein Name
Programmed cell death protein 1
UniProt Gene Name
Pdcd1
UniProt Synonym Gene Names
Pd1; Protein PD-1; mPD-1
UniProt Entry Name
PDCD1_MOUSE

Uniprot Description

PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse 'exhausted' T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells.

Protein type: Apoptosis; Membrane protein, integral

Cellular Component: external side of plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: negative regulation of apoptosis; negative regulation of tolerance induction; positive regulation of apoptosis

Similar Products

Product Notes

The PD-1 pdcd1 (Catalog #AAA8400034) is an Antibody produced from Human and is intended for research purposes only. The product is available for immediate purchase. The Anti-PD-1 (Nivolumab) Biotinylated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PD-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1ug. Researchers should empirically determine the suitability of the PD-1 pdcd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PD-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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