Western Blot (WB)
(Sample Data: Representative western blot (1:2500) using 10ug, 20ug, and 30ug of Jurkat cell lysate.)
Mouse p38 alpha Monoclonal Antibody | anti-p38alpha antibody
Anti-p38 alpha
Reactivity
p38a from Human, Mouse
Applications
Western Blot
Purity
Affinity purified using Protein G
Synonyms
p38 alpha; Monoclonal Antibody; Anti-p38 alpha; anti-p38alpha antibody
Host
Mouse
Reactivity
p38a from Human, Mouse
Clonality
Monoclonal
Clone Number
9F12
Specificity
Anti-p38alpha antibody recognizes the p38alpha protein.
Purity/Purification
Affinity purified using Protein G
Form/Format
0.1M TRIS pH8.0, 0.1M glycine
Applicable Applications for anti-p38alpha antibody
Western Blot (WB)
Application Notes
WB: 19326:20325
Immunogen
Recombinant full length active p38alpha protein
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.
Western Blot (WB)
(Sample Data: Representative western blot (1:2500) using 10ug, 20ug, and 30ug of Jurkat cell lysate.)
Western Blot (WB)
(Sample Data: Representative western blot (1:2500) using 10ug, 20ug, and 30ug of Jurkat cell lysate.)
Related Product Information for anti-p38alpha antibody
p38alpha (SAPK2A) is a member of the p38 MAPK family which are activated by various environmental stresses and proinflammatory cytokines (1). The activation of p38 requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase (2). The substrates of p38 include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Product Categories/Family for anti-p38alpha antibody
References
1. Han, J. et al: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265: 808-811, 1994.
2. Ge, B. et al: MAPKK-independent activation of p38-alpha mediated by TAB1-dependent autophosphorylation of p38-alpha. Science 295: 1291-1294, 2002.
2. Ge, B. et al: MAPKK-independent activation of p38-alpha mediated by TAB1-dependent autophosphorylation of p38-alpha. Science 295: 1291-1294, 2002.
Similar Products
Product Notes
The p38alpha (Catalog #AAA516098) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-p38 alpha reacts with p38a from Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's p38 alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 19326:20325. Researchers should empirically determine the suitability of the p38alpha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p38 alpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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