Western Blot (WB)
(Host: RabbitTarget Name: CHD3Sample Tissue: Human 293T Whole Cell lysatesAntibody Dilution: 3ug/ml)
Rabbit anti-Human CHD3 Polyclonal Antibody | anti-CHD3 antibody
CHD3 Antibody-C-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: CHD3Sample Tissue: Human 293T Whole Cell lysatesAntibody Dilution: 3ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: CHD3Sample Tissue: Human 293T Whole Cell lysatesAntibody Dilution: 3ug/ml)
NCBI and Uniprot Product Information
Uniprot Description
CHD-3 iso3: Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. Central component of the nucleosome remodeling and histone deacetylase (NuRD) repressive complex. Interacts with TRIM28 and SERBP1. Interacts (via its C-terminal) with HABP4. Interacts with PCNT; the interaction regulates centrosome integrity. Widely expressed. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Helicase; EC 3.6.4.12
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: nucleoplasm; centrosome; intermediate filament cytoskeleton; cytoplasm; nucleolus; NuRD complex; nucleus
Molecular Function: ATP-dependent DNA helicase activity; protein binding; DNA binding; zinc ion binding; helicase activity; ATP binding
Biological Process: chromatin assembly or disassembly; regulation of transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription, DNA-dependent; centrosome organization and biogenesis; chromatin modification; spindle organization and biogenesis; DNA duplex unwinding
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Product Notes
The CHD3 chd3 (Catalog #AAA3249593) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHD3 Antibody-C-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CHD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CHD3 chd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: RKKRDSEEEF GSERDEYREK SESGGSEYGT GPGRKRRRKH REKKEKKTKR. It is sometimes possible for the material contained within the vial of "CHD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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