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Western Blot (WB) (Western Blot analysis of Human brain tissue using NCALD Monoclonal Antibody at dilution of 1:1000)

Mouse anti-Human NCALD Monoclonal Antibody | anti-NCALD antibody

NCALD Monoclonal Antibody

Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein A purification
Synonyms
NCALD; Monoclonal Antibody; NCALD Monoclonal Antibody; MGC33870; MGC74858; Neurocalcin delta; Neurocalcin-delta; anti-NCALD antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
213
Purity/Purification
Protein A purification
Concentration
1mg/mL (varies by lot)
Sequence Length
193
Applicable Applications for anti-NCALD antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:5000
IHC: 1:20-1:200
Immunogen
Fusion protein of NCALD
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Human brain tissue using NCALD Monoclonal Antibody at dilution of 1:1000)

Western Blot (WB) (Western Blot analysis of Human brain tissue using NCALD Monoclonal Antibody at dilution of 1:1000)
Related Product Information for anti-NCALD antibody
NCALD(Neurocalcin-delta) is a member of the EF-hand calcium-binding protein superfamily. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. It is a high-affinityCa2+ sensor (Kd of approx. 0.6 uM), which is most abundantly expressed in the Purkinje cells of the cerebellum. This antibody is specific to NCALD.
Product Categories/Family for anti-NCALD antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 22kDa
Observed: 22kDa
NCBI Official Full Name
neurocalcin-delta
NCBI Official Synonym Full Names
neurocalcin delta
NCBI Official Symbol
NCALD
NCBI Protein Information
neurocalcin-delta
UniProt Protein Name
Neurocalcin-delta
Protein Family
UniProt Gene Name
NCALD

NCBI Description

This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.

Research Articles on NCALD

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Product Notes

The NCALD ncald (Catalog #AAA2541994) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NCALD Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NCALD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:5000 IHC: 1:20-1:200. Researchers should empirically determine the suitability of the NCALD ncald for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NCALD, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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