Western Blot (WB)
(All lanes : Anti-SPCS1 Antibody (Center) at 1:2000 dilutionLane 1: HT-1080 whole cell lysateLane 2: T47D whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human SPCS1 Polyclonal Antibody | anti-SPCS1 antibody
SPCS1 Antibody (Center)
Western Blot (WB)
(All lanes : Anti-SPCS1 Antibody (Center) at 1:2000 dilutionLane 1: HT-1080 whole cell lysateLane 2: T47D whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-SPCS1 Antibody (Center) at 1:2000 dilutionLane 1: HT-1080 whole cell lysateLane 2: T47D whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
NCBI and Uniprot Product Information
NCBI Description
SPCS1: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.
Protein type: Membrane protein, multi-pass; EC 3.4.-.-; Cofactor and Vitamin Metabolism - biotin; Amino Acid Metabolism - lysine degradation; Protease; Endoplasmic reticulum; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; signal peptidase complex
Molecular Function: peptidase activity; protein binding
Biological Process: SRP-dependent cotranslational protein targeting to membrane; protein targeting to ER; cellular protein metabolic process; translation; signal peptide processing; gene expression; proteolysis; regulation of insulin secretion
Uniprot Description
SPCS1: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.
Protein type: EC 3.4.-.-; Amino Acid Metabolism - lysine degradation; Membrane protein, integral; Cofactor and Vitamin Metabolism - biotin; Protease; Membrane protein, multi-pass; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; signal peptidase complex
Molecular Function: peptidase activity; protein binding
Biological Process: cellular protein metabolic process; gene expression; protein targeting to ER; proteolysis; regulation of insulin secretion; signal peptide processing; SRP-dependent cotranslational protein targeting to membrane; translation
Research Articles on SPCS1
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Product Notes
The SPCS1 spcs1 (Catalog #AAA9216271) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPCS1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPCS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:2000. Researchers should empirically determine the suitability of the SPCS1 spcs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPCS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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