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Western Blot (WB) (Figure-1: Western blot analysis of MHC classII. Anti-MHC classII antibody (Clone: ABM56C9) was tested at 4 ug/ml on h Spleen lysate.)

Mouse anti-Human MHC Class II Monoclonal Antibody | anti-HLA-DMA antibody

Monoclonal antibody to MHC Class II (Clone: ABM56C9)

Gene Names
HLA-DMA; DMA; HLADM; RING6; D6S222E
Reactivity
Human
Applications
Western Blot
Purity
Protein G Chromatography
Synonyms
MHC Class II; Monoclonal Antibody; Monoclonal antibody to MHC Class II (Clone: ABM56C9); Anti-MHC classII Antibody; ABM56C9; HLA-DMA; Cancer Marker; Monoclonal antibody to MHC classII (Clone: ABM56C9); MHC classII; P28067; MHC class II antigen DMA; Really interesting new gene 6 protein; DMA; RING6; Anti MHC classII Antibody; MHC classII Antibody; anti-HLA-DMA antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
ABM56C9
Purity/Purification
Protein G Chromatography
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
261
Applicable Applications for anti-HLA-DMA antibody
Western Blot (WB)
Application Notes
WB: 4-6 ug/ml
Antigen
MHC classII
Immunogen Information
A partial length recombinant MHC classII protein (amino acids 20-240) was used as the immunogen for this antibody.
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.

Western Blot (WB)

(Figure-1: Western blot analysis of MHC classII. Anti-MHC classII antibody (Clone: ABM56C9) was tested at 4 ug/ml on h Spleen lysate.)

Western Blot (WB) (Figure-1: Western blot analysis of MHC classII. Anti-MHC classII antibody (Clone: ABM56C9) was tested at 4 ug/ml on h Spleen lysate.)
Product Categories/Family for anti-HLA-DMA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
HLA class II histocompatibility antigen, DM alpha chain
NCBI Official Synonym Full Names
major histocompatibility complex, class II, DM alpha
NCBI Official Symbol
HLA-DMA
NCBI Official Synonym Symbols
DMA; HLADM; RING6; D6S222E
NCBI Protein Information
HLA class II histocompatibility antigen, DM alpha chain
UniProt Protein Name
HLA class II histocompatibility antigen, DM alpha chain
UniProt Gene Name
HLA-DMA
UniProt Synonym Gene Names
DMA; RING6
UniProt Entry Name
DMA_HUMAN

NCBI Description

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Research Articles on HLA-DMA

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Product Notes

The HLA-DMA hla-dma (Catalog #AAA669317) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal antibody to MHC Class II (Clone: ABM56C9) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MHC Class II can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 4-6 ug/ml. Researchers should empirically determine the suitability of the HLA-DMA hla-dma for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MHC Class II, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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