Testing Data
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Rabbit ZMAT3 Polyclonal Antibody | anti-ZMAT3 antibody
ZMAT3 (Zinc Finger Matrin-type Protein 3, WIG1, WIG-1, PAG608) (Biotin)
Applications are based on unconjugated antibody.
Testing Data
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Testing Data
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NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008]
Uniprot Description
ZMAT3: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus
Chromosomal Location of Human Ortholog: 3q26.32
Cellular Component: nucleolus
Molecular Function: protein binding; zinc ion binding
Biological Process: protein transport; positive regulation of apoptosis; apoptosis; regulation of growth; response to DNA damage stimulus
Research Articles on ZMAT3
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Product Notes
The ZMAT3 zmat3 (Catalog #AAA6443834) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZMAT3 (Zinc Finger Matrin-type Protein 3, WIG1, WIG-1, PAG608) (Biotin) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZMAT3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:2000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ZMAT3 zmat3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZMAT3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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