Mouse anti-Mouse MHC Class 1, H-2Kb Monoclonal Antibody | anti-H2-K1 antibody

MHC Class 1, H-2Kb (MHC Class I H-2Kb, H-2 Class I Histocompatibility Antigen K-B alpha Chain, H-2K(B), H2-K1, H-2K, H2-K, H-2K(d), MGC7052, MGC184092) (FITC)

Cat. Num. AAA633611

• Gene Names: H2-K1; K-f; H-2K; H2-K; H-2K(d); MGC7052; MGC184092
• Reactivity: Mouse
• Applications: Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by affinity chromatography
• Synonyms: MHC Class 1; H-2Kb; Monoclonal Antibody; H-2Kb (MHC Class I H-2Kb; H-2 Class I Histocompatibility Antigen K-B alpha Chain; H-2K(B); H2-K1; H-2K; H2-K; H-2K(d); MGC7052; MGC184092) (FITC); Anti -MHC Class 1; anti-H2-K1 antibody

• Host: Mouse
• Reactivity: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone Number: AF6-88.5
• Specificity: Recognizes the H-2Kb determinant present on all nucleated cells of mice expressing this MHC class I haplotype. Does not cross react with other haplotypes.
• Purity/Purification: Affinity Purified; Purified by affinity chromatography
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).

• Applicable Applications for anti-H2-K1 antibody: Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Flow Cytometry.; Dilution: Flow Cytometry: 1:10-1:20; 10ul labels 10e6 cells in 100ul
• Immunogen: C57BL mouse splenocytes
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.

Related Product Information for anti-H2-K1 antibody

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region. There are 3 major MHC class I proteins encoded by the H-2 which are H-2K, H-2L and H-2D. The H- 2K gene is part of the murine H-2 complex on chromosome 17 and there are a large number of variant alleles of this gene.

Product Categories/Family for anti-H2-K1 antibody

Antibodies; Abs to MHC

NCBI and Uniprot Product Information

• NCBI GI #: 5531260
• NCBI GeneID: 14972
• UniProt Accession #: P01901; O19449; O19468; O35641; P01902; P03991; P04223; P14428; Q1XIR8; Q31141
• Molecular Weight: 41,302 Da
• NCBI Official Full Name: MHC class I antigen H-2K
• NCBI Official Synonym Full Names: histocompatibility 2, K1, K region
• NCBI Official Symbol: H2-K1
• NCBI Official Synonym Symbols: K-f; H-2K; H2-K; H-2K(d); MGC7052; MGC184092
• NCBI Protein Information: H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K(B); H-2K(K); H-2K(Q); MHC class I antigen; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen; class I major histocompatibility antigen H-2Kd; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain
• UniProt Protein Name: H-2 class I histocompatibility antigen, K-B alpha chain
• Protein Family: H-2 class I histocompatibility antigen
• UniProt Gene Name: H2-K1
• UniProt Synonym Gene Names: H2-K
• UniProt Entry Name: HA1B_MOUSE

Uniprot Description

HLAC iso22: Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: Golgi apparatus; cell surface; membrane; endoplasmic reticulum; integral to membrane; MHC class I protein complex; Golgi medial cisterna; external side of plasma membrane

Molecular Function: protein binding; peptide antigen binding; beta-2-microglobulin binding; protein heterodimerization activity; T cell receptor binding; peptide binding; TAP binding; receptor binding

Biological Process: antigen processing and presentation; antigen processing and presentation of peptide antigen via MHC class I; immune system process; positive regulation of T cell mediated cytotoxicity; defense response to bacterium; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; inner ear development; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent