Western Blot (WB)
(Western Blot detection against Immunogen (32.93kD).)
Mouse anti-Human MAPRE2 Monoclonal Antibody | anti-MAPRE2 antibody
MAPRE2 (Microtubule-associated Protein RP/EB Family Member 2, APC-binding Protein EB2, End-binding Protein 2, EB2, RP1)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: Immunofluorescence: 35ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml
Western Blot (WB)
(Western Blot detection against Immunogen (32.93kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (32.93kD).)
Western Blot (WB)
(MAPRE2 monoclonal antibody Western Blot analysis of MAPRE2 expression in K-562.)
Western Blot (WB)
(MAPRE2 monoclonal antibody Western Blot analysis of MAPRE2 expression in K-562.)
Western Blot (WB)
(Western Blot analysis of MAPRE2 expression in transfected 293T cell line by MAPRE2 monoclonal antibody |Lane 1: MAPRE2 transfected lysate (37kD).|Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of MAPRE2 expression in transfected 293T cell line by MAPRE2 monoclonal antibody |Lane 1: MAPRE2 transfected lysate (37kD).|Lane 2: Non-transfected lysate.)
Immunohistochemistry (IHC)
(Immunoperoxidase of monoclonal antibody to MAPRE2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3ug/ml].)
Immunohistochemistry (IHC)
(Immunoperoxidase of monoclonal antibody to MAPRE2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3ug/ml].)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to MAPRE2 on HeLa cell. [antibody concentration 35ug/ml].)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to MAPRE2 on HeLa cell. [antibody concentration 35ug/ml].)
NCBI and Uniprot Product Information
Uniprot Description
Function: May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration
By similarity.
Subunit structure: Interacts with DCTN1. Binds to the C-terminal domain of APC. Binds monomeric and polymerized tubulin. Ref.1 Ref.9 Ref.10
Subcellular location: Cytoplasm › cytoskeleton. Note: Associated with the microtubule network. Accumulates at the plus end of microtubules. Ref.9
Tissue specificity: Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes. Ref.1
Domain: Composed of two functionally independent domains. The N-terminal domain forms a hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
Sequence similarities: Belongs to the MAPRE family.Contains 1 CH (calponin-homology) domain.Contains 1 EB1 C-terminal domain.
Sequence caution: The sequence BAA83375.1 differs from that shown. Reason: Erroneous initiation.
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Product Notes
The MAPRE2 mapre2 (Catalog #AAA648443) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MAPRE2 (Microtubule-associated Protein RP/EB Family Member 2, APC-binding Protein EB2, End-binding Protein 2, EB2, RP1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAPRE2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry. Dilution: Immunofluorescence: 35ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml. Researchers should empirically determine the suitability of the MAPRE2 mapre2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MPGPTQTLSP NGENNNDIIQ DNNGTIIPFR KHTVRGERSY SWGMAVNVYS TSITQETMSR HD. It is sometimes possible for the material contained within the vial of "MAPRE2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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