Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer's manual (BD Pharmingen'), stained with PE-conjugated anti-Human LILRA3(CD85e). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.)
Rabbit anti-Human LILRA3 Monoclonal Antibody | anti-LILRA3 antibody
Recombinant Anti-LILRA3 Antibody (PE), Rabbit Monoclonal
Gene Names
LILRA3; HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
LILRA3; Monoclonal Antibody; Recombinant Anti-LILRA3 Antibody (PE); Rabbit Monoclonal; LILRA3/CD85e/ILT6 Antibody (PE); Rabbit MAb; leukocyte immunoglobulin like receptor A3; Anti-CD85e Antibody; Anti-HM31 Antibody; Anti-HM43 Antibody; Anti-ILT-6 Antibody; Anti-ILT6 Antibody; Anti-LIR-4 Antibody; Anti-LIR4 Antibody; anti-LILRA3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
060
Specificity
Human LILRA3/CD85e/ILT6
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Concentration
10ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-LILRA3 antibody
Flow Cytometry (FC/FACS/FCM)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human LILRA3/CD85e/ILT6 Protein
Conjugation
PE
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human LILRA3/CD85e/ILT6 (rh LILRA3/CD85e/ILT6) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer's manual (BD Pharmingen'), stained with PE-conjugated anti-Human LILRA3(CD85e). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LILRA3(CD85e) expression on human whole blood monocytes. The cells were treated according to manufacturer's manual (BD Pharmingen'), stained with PE-conjugated anti-Human LILRA3(CD85e). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.)
Related Product Information for anti-LILRA3 antibody
ILT6, also known as LILRA3, belongs to the ILT family. In humans, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immunoglobulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
Product Categories/Family for anti-LILRA3 antibody
References
Wi?niewski A, et al. (2004) Distribution of LILRA3 (ILT6/LILRA3/LIR4) deletion in psoriatic patients and healthy controls. Hum Immunol. 64(4):458-61. Norman PJ, et al. (2003) DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3. Immunogenetics. 55(3):165-71. Cella M, et al. (1997) A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med. 185(10): 1743-51.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
49,187 Da
NCBI Official Full Name
Leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
NCBI Official Synonym Full Names
leukocyte immunoglobulin like receptor A3
NCBI Official Symbol
LILRA3
NCBI Official Synonym Symbols
HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily A member 3
Protein Family
NCBI Description
This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]
Research Articles on LILRA3
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Product Notes
The LILRA3 (Catalog #AAA8106997) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-LILRA3 Antibody (PE), Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LILRA3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the LILRA3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LILRA3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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