Testing Data
(HUVEC cells were stained with PE-conjugated anti-human Integrin αVβ3, filled histogram or isotype control, open histogram.)
Mouse anti-Human Integrin alphaV, beta3 Monoclonal Antibody | anti-ITGB3 antibody
Integrin alphaV, beta3 (PE)
Gene Names
ITGB3; CD61
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Integrin alphaV; beta3; Monoclonal Antibody; beta3 (PE); Anti -Integrin alphaV; anti-ITGB3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8H127
Specificity
Recognizes human Integrin alphaVBeta3.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide. Labeled with PE.
Applicable Applications for anti-ITGB3 antibody
Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: Use 10ul to label 10e6 cells.
Dilution: Flow Cytometry: Use 10ul to label 10e6 cells.
Immunogen
Human osteoclasts
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Testing Data
(HUVEC cells were stained with PE-conjugated anti-human Integrin αVβ3, filled histogram or isotype control, open histogram.)
Testing Data
(HUVEC cells were stained with PE-conjugated anti-human Integrin αVβ3, filled histogram or isotype control, open histogram.)
Related Product Information for anti-ITGB3 antibody
The Integrin alphaV (CD51) subunit is a transmembrane protein that associates with Integrin Beta1 (CD29), Beta5, and Beta6 subunits. Integrin alphaVBeta3 heterodimers are expressed by melanoma cells, endothelial cells, and osteoclasts, and at very low levels by platelets. The complex mediates adhesion to fibrinogen, fibronectin, vitronectin, and thrombospondin.
Product Categories/Family for anti-ITGB3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
integrin beta-3
NCBI Official Symbol
ITGB3
NCBI Official Synonym Symbols
CD61
NCBI Protein Information
integrin beta-3; beta3 integrin; integrin beta 3; glycoprotein GPIIIa
Protein Family
Research Articles on ITGB3
Similar Products
Product Notes
The ITGB3 (Catalog #AAA603806) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Integrin alphaV, beta3 (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin alphaV, beta3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry. Dilution: Flow Cytometry: Use 10ul to label 10e6 cells. Researchers should empirically determine the suitability of the ITGB3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin alphaV, beta3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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