Testing Data
(CD131 transfected cell stained with MBS6004462, followed by anti-mouse IgG FITC.)
Mouse anti-Human IL3RB Monoclonal Antibody | anti-Csf2rb2 antibody
IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)
Gene Names
Csf2rb2; Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb
Reactivity
Human
Applications
Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
IL3RB; Monoclonal Antibody; IL3RB (CD131; Cytokine Receptor Common Subunit beta; CDw131; GM-CSF/IL-3/IL-5 Receptor Common beta Subunit; CSF2RB; IL5RB); Anti -IL3RB (CD131; anti-Csf2rb2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
1C1
Specificity
Recognizes human CD131.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-Csf2rb2 antibody
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry, Western Blot and Immunoprecipitation.
Dilution: Flow Cytometry: 0.5ug/10e5 cells in 100ul
Dilution: Flow Cytometry: 0.5ug/10e5 cells in 100ul
Immunogen
Human IL-3R B chain transfected COS cells
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Testing Data
(CD131 transfected cell stained with MBS6004462, followed by anti-mouse IgG FITC.)
Testing Data
(CD131 transfected cell stained with MBS6004462, followed by anti-mouse IgG FITC.)
Related Product Information for anti-Csf2rb2 antibody
CD131, also known as the IL-3R common B subunit (BC), is a 95-120kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common B subunit associates with the specific a subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. This antibody is a non-Blocking antibody.
Product Categories/Family for anti-Csf2rb2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97,195 Da
NCBI Official Full Name
interleukin-3 receptor class 2 subunit beta
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
NCBI Official Symbol
Csf2rb2
NCBI Official Synonym Symbols
Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb
NCBI Protein Information
interleukin-3 receptor class 2 subunit beta; IL-3R class 2 subunit beta; IL-3 receptor class 2 subunit beta; interleukin-3 receptor class II beta chain; colony-stimulating factor 2 receptor subunit beta-2
UniProt Protein Name
Interleukin-3 receptor class 2 subunit beta
Protein Family
UniProt Gene Name
Csf2rb2
UniProt Synonym Gene Names
Ai2ca; Il3r; Il3rb2; IL-3 receptor class 2 subunit beta
UniProt Entry Name
IL3B2_MOUSE
Uniprot Description
CSF2RB iso2: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.
Protein type: Membrane protein, integral; Receptor, cytokine
Cellular Component: membrane; plasma membrane; integral to membrane
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity
Biological Process: cytokine and chemokine mediated signaling pathway
Research Articles on Csf2rb2
Similar Products
Product Notes
The Csf2rb2 csf2rb2 (Catalog #AAA6004462) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL3RB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Dilution: Flow Cytometry: 0.5ug/10e5 cells in 100ul. Researchers should empirically determine the suitability of the Csf2rb2 csf2rb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL3RB, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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