Western Blot (WB)
(Western Blot analysis of various samples using CASP9 Polyclonal Antibody at dilution of 1:1000.)
Rabbit anti-Mouse, Rat CASP9 Polyclonal Antibody | anti-CASP9 antibody
CASP9 Polyclonal Antibody
Gene Names
Casp9; Mch6; APAF-3; CASP-9; AI115399; AW493809; ICE-LAP6; Caspase-9
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Affinity Purification
Synonyms
CASP9; Polyclonal Antibody; CASP9 Polyclonal Antibody; APAF-3; APAF3; Apoptosis related cysteine peptidase; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP-9; Caspase 9 apoptosis related cysteine peptidase; Caspase 9 Dominant Negative; Caspase 9c; Caspase-9; Caspase-9 subunit p10; ICE LAP6; ICE like apoptotic protease 6; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1; regulatory subunit 56; RNCASP9; anti-CASP9 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Concentration
1.3 mg/mL (varies by lot)
Sequence Length
454
Applicable Applications for anti-CASP9 antibody
Western Blot (WB)
Application Notes
WB: 1:800-1:1000
Immunogen
Recombinant protein corresponding to Mouse Caspase9
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of various samples using CASP9 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of various samples using CASP9 Polyclonal Antibody at dilution of 1:1000.)
Related Product Information for anti-CASP9 antibody
Caspase 9, apoptosis-related cysteine protease (CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Capase 9 is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade.
Product Categories/Family for anti-CASP9 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 35/46kDa
Observed: 35/46kDa
Observed: 35/46kDa
NCBI Official Full Name
caspase-9 isoform 1
NCBI Official Synonym Full Names
caspase 9
NCBI Official Symbol
Casp9
NCBI Official Synonym Symbols
Mch6; APAF-3; CASP-9; AI115399; AW493809; ICE-LAP6; Caspase-9
NCBI Protein Information
caspase-9
UniProt Protein Name
Caspase-9
Protein Family
UniProt Gene Name
Casp9
UniProt Synonym Gene Names
Mch6; CASP-9; APAF-3; ICE-LAP6
NCBI Description
This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]
Uniprot Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) ().
Research Articles on CASP9
Similar Products
Product Notes
The CASP9 casp9 (Catalog #AAA2556348) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASP9 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CASP9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:800-1:1000. Researchers should empirically determine the suitability of the CASP9 casp9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASP9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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