Immunohistochemistry (IHC)
(CSF2RB/CD131(10ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human spleen, neutrophils,followed by biotinylated goat, rabbit IgG, alkaline phosphatase-streptavidin and chromogen.)
Rabbit anti-Mouse, Rat IL3RB Polyclonal Antibody | anti-Csf2rb2 antibody
IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)
Gene Names
Csf2rb2; Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb
Reactivity
Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
IL3RB; Polyclonal Antibody; IL3RB (CD131; Cytokine Receptor Common Subunit beta; CDw131; GM-CSF/IL-3/IL-5 Receptor Common beta Subunit; CSF2RB; IL5RB); Anti -IL3RB (CD131; anti-Csf2rb2 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CSF2RB/CD131. Species Crossreactivity: Mouse, rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Applicable Applications for anti-Csf2rb2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:1000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Dilution: ELISA: 1:1000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Immunogen
Synthetic peptide corresponding to human CSF2RB/CD131.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunohistochemistry (IHC)
(CSF2RB/CD131(10ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human spleen, neutrophils,followed by biotinylated goat, rabbit IgG, alkaline phosphatase-streptavidin and chromogen.)
Immunohistochemistry (IHC)
(CSF2RB/CD131(10ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human spleen, neutrophils,followed by biotinylated goat, rabbit IgG, alkaline phosphatase-streptavidin and chromogen.)
Western Blot (WB)
(Western blot analysis of extracts from Raw264.7 cells, treated with G -CSF 25ng/ml 15', using IL-3R beta. The lane on the right is treated with the synthesized peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Raw264.7 cells, treated with G -CSF 25ng/ml 15', using IL-3R beta. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-Csf2rb2 antibody
CSF2RB is a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defective CSF2RB has been reported to be associated with protein alveolar proteinosis.
Product Categories/Family for anti-Csf2rb2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97,195 Da
NCBI Official Full Name
interleukin-3 receptor class 2 subunit beta
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
NCBI Official Symbol
Csf2rb2
NCBI Official Synonym Symbols
Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb
NCBI Protein Information
interleukin-3 receptor class 2 subunit beta; IL-3R class 2 subunit beta; IL-3 receptor class 2 subunit beta; interleukin-3 receptor class II beta chain; colony-stimulating factor 2 receptor subunit beta-2
UniProt Protein Name
Interleukin-3 receptor class 2 subunit beta
Protein Family
UniProt Gene Name
Csf2rb2
UniProt Synonym Gene Names
Ai2ca; Il3r; Il3rb2; IL-3 receptor class 2 subunit beta
UniProt Entry Name
IL3B2_MOUSE
Uniprot Description
Function: In mouse, there are two classes of high-affinity IL3 receptors. One contains this IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors.
Subunit structure: Heterodimer of an alpha and a beta subunit.
Subcellular location: Membrane; Single-pass type I membrane protein.
Domain: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The box 1 motif is required for JAK interaction and/or activation.
Sequence similarities: Belongs to the type I cytokine receptor family. Type 4 subfamily.Contains 2 fibronectin type-III domains.
Research Articles on Csf2rb2
Similar Products
Product Notes
The Csf2rb2 csf2rb2 (Catalog #AAA647780) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IL3RB can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: ELISA: 1:1000 Western Blot: 1:500-1:1000 Immunohistochemistry (Paraffin): 10ug/ml. Researchers should empirically determine the suitability of the Csf2rb2 csf2rb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL3RB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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