Mouse anti-Human IL-19 Monoclonal Antibody | anti-IL19 antibody
Anti-IL-19 Antibody, Mouse Monoclonal
Gene Names
IL19; MDA1; NG.1; ZMDA1; IL-10C
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
IL-19; Monoclonal Antibody; Anti-IL-19 Antibody; Mouse Monoclonal; IL19/Interleukin-19 Antibody; Mouse MAb; interleukin 19; Anti-IL-10C Antibody; Anti-Interleukin-19 Antibody; Anti-MDA1 Antibody; Anti-NG.1 Antibody; Anti-ZMDA1 Antibody; anti-IL19 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
11
Specificity
Human IL19/Interleukin-19
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-IL19 antibody
ELISA (EIA) (Cap)
Application Notes
ELISA (Cap): This antibody will detect Human IL19/Interleukin-19 in ELISA pair set.
In a sandwich ELISA, it can be used as capture antibody.
In a sandwich ELISA, it can be used as capture antibody.
Immunogen
Recombinant Human IL19/Interleukin-19 Protein
Conjugation
Unconjugated
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL19/Interleukin-19 (rh IL19/Interleukin-19). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-IL19 antibody
The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
23,079 Da
NCBI Official Full Name
melanoma differentiation associated protein-like protein
NCBI Official Synonym Full Names
interleukin 19
NCBI Official Symbol
IL19
NCBI Official Synonym Symbols
MDA1; NG.1; ZMDA1; IL-10C
NCBI Protein Information
interleukin-19
Protein Family
NCBI Description
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Research Articles on IL19
Similar Products
Product Notes
The IL19 (Catalog #AAA8106700) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL-19 Antibody, Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL-19 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA) (Cap). ELISA (Cap): This antibody will detect Human IL19/Interleukin-19 in ELISA pair set. In a sandwich ELISA, it can be used as capture antibody. Researchers should empirically determine the suitability of the IL19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-19, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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