Western Blot (WB)
(Western Blot analysis of HepG2 cells using IFITM2-specific Monoclonal Antibody at dilution of 1:1000)
Mouse anti-Human IFITM2 Monoclonal Antibody | anti-IFITM2 antibody
IFITM2 Monoclonal Antibody
Gene Names
IFITM2; 1-8D; DSPA2c
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Protein G purification
Synonyms
IFITM2; Monoclonal Antibody; IFITM2 Monoclonal Antibody; 1 8D; Dispanin subfamily A member 2c; DSPA2c; IFITM 2; Interferon induced transmembrane protein 2 (1 8D); Interferon induced transmembrane protein 2; Interferon inducible protein 1 8D; IFITM2-specific; anti-IFITM2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
12
Purity/Purification
Protein G purification
Concentration
1mg/mL (varies by lot)
Sequence Length
132
Applicable Applications for anti-IFITM2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:5000
Immunogen
Fusion protein
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of HepG2 cells using IFITM2-specific Monoclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of HepG2 cells using IFITM2-specific Monoclonal Antibody at dilution of 1:1000)
Related Product Information for anti-IFITM2 antibody
IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. This antibody is specific to IFTIM2.
Product Categories/Family for anti-IFITM2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 15kDa
NCBI Official Full Name
interferon-induced transmembrane protein 2
NCBI Official Synonym Full Names
interferon induced transmembrane protein 2
NCBI Official Symbol
IFITM2
NCBI Official Synonym Symbols
1-8D; DSPA2c
NCBI Protein Information
interferon-induced transmembrane protein 2
UniProt Protein Name
Interferon-induced transmembrane protein 2
Protein Family
UniProt Gene Name
IFITM2
UniProt Synonym Gene Names
DSPA2c
Uniprot Description
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
Research Articles on IFITM2
Similar Products
Product Notes
The IFITM2 ifitm2 (Catalog #AAA2541944) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IFITM2 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IFITM2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:5000. Researchers should empirically determine the suitability of the IFITM2 ifitm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFITM2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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