Testing Data
(Immunocytochemistry stain of Hela using HSPB1 antibody (1:300).)
Mouse HSPB1 Monoclonal Antibody | anti-HSPB1 antibody
HSPB1 (Hsp27) Antibody
Testing Data
(Immunocytochemistry stain of Hela using HSPB1 antibody (1:300).)
Testing Data
(Immunocytochemistry stain of Hela using HSPB1 antibody (1:300).)
Testing Data #2
(Western blot detection of HSPB1 in Hela, HsHela, A431, COS7, LNCAP&MCF7 cell lysates and using HSPB1 antibody (1:1000 diluted). Predicted band size: 23KDa Observed band size:27KDa.)
Testing Data #2
(Western blot detection of HSPB1 in Hela, HsHela, A431, COS7, LNCAP&MCF7 cell lysates and using HSPB1 antibody (1:1000 diluted). Predicted band size: 23KDa Observed band size:27KDa.)
Entrez Summary: The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
Uniprot Description
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).
Research Articles on HSPB1
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Product Notes
The HSPB1 hspb1 (Catalog #AAA857774) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HSPB1 (Hsp27) Antibody reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's HSPB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the HSPB1 hspb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSPB1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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