Immunohistochemistry (IHC)-Formalin
(Formalin-fixed, paraffin-embedded human breast stained with HOMEZ Mouse Monoclonal Antibody (PCRP-HOMEZ-1B5). )
Mouse anti-Human Homeobox and Leucine Zipper Encoding/HOMEZ Monoclonal Antibody | anti-HOMEZ antibody
Homeobox and Leucine Zipper Encoding/HOMEZ Mouse Monoclonal Antibody [Clone PCRP-HOMEZ-1B5]
Gene Names
HOMEZ; KIAA1443
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Synonyms
Homeobox and Leucine Zipper Encoding/HOMEZ; Monoclonal Antibody; Homeobox and Leucine Zipper Encoding/HOMEZ Mouse Monoclonal Antibody [Clone PCRP-HOMEZ-1B5]; KIAA1443; Homeodomain leucine zipper-containing factor; anti-HOMEZ antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2a
Clone Number
PCRP-HOMEZ-1B5
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-HOMEZ antibody
Flow Cytometry (FC/FACS), Immunohistochemistry-Formalin (IHC-F)
Application Notes
FC/FACS: 1-2ug/million cells
IHC (Formalin-fixed): 1-2ug/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH9.0, for 45 minutes at 95 degree C followed by cooling at RT for 20 minutes)
IHC (Formalin-fixed): 1-2ug/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH9.0, for 45 minutes at 95 degree C followed by cooling at RT for 20 minutes)
Immunogen
Recombinant full-length human HOMEZ protein
Cellular Localization
Nucleus
Positive Control
Human testis, kidney or fetal lung.
Hu-chromosome Location
14q11.2
Unigene
632332
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Immunohistochemistry (IHC)-Formalin
(Formalin-fixed, paraffin-embedded human breast stained with HOMEZ Mouse Monoclonal Antibody (PCRP-HOMEZ-1B5). )
Immunohistochemistry (IHC)-Formalin
(Formalin-fixed, paraffin-embedded human breast stained with HOMEZ Mouse Monoclonal Antibody (PCRP-HOMEZ-1B5). )
Related Product Information for anti-HOMEZ antibody
Homeodomain-containing proteins function as transcription factors that typically switch on cascades of other genes. Usually homeodomain proteins act in the promoter region of their target genes as complexes with other transcription factors, leading to much higher target specificity than a single homeodomain protein. HOMEZ (Homeobox and leucine zipper protein) is a 525 amino acid nuclear protein that contains 3 atypical homeodomains, 2 leucine zipper-like motifs, proline and serine-rich motifs and an acidic domain. Within homeodomain 2, it contains a putative nuclear localization signal. HOMEZ shares significant sequence similarity with mouse ZHX1 and sequences that are homologous to HOMEZ are restricted to vertebrates. Likely functioning as a transcription regulator, HOMEZ is ubiquitously expressed with highest levels found in in ovary, testis, kidney, fetal lung and kidney.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
61,695 Da
NCBI Official Full Name
KIAA1443, isoform CRA_c
NCBI Official Synonym Full Names
homeobox and leucine zipper encoding
NCBI Official Symbol
HOMEZ
NCBI Official Synonym Symbols
KIAA1443
NCBI Protein Information
homeobox and leucine zipper protein Homez
UniProt Protein Name
Homeobox and leucine zipper protein Homez
Protein Family
UniProt Gene Name
HOMEZ
UniProt Synonym Gene Names
KIAA1443
UniProt Entry Name
HOMEZ_HUMAN
Uniprot Description
HOMEZ: May function as a transcriptional regulator.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: cytoplasm; nucleolus; nucleus
Molecular Function: DNA binding; transcription factor activity; transcription corepressor activity
Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter
Research Articles on HOMEZ
Similar Products
Product Notes
The HOMEZ homez (Catalog #AAA4382164) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Homeobox and Leucine Zipper Encoding/HOMEZ Mouse Monoclonal Antibody [Clone PCRP-HOMEZ-1B5] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Homeobox and Leucine Zipper Encoding/HOMEZ can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry-Formalin (IHC-F). FC/FACS: 1-2ug/million cells IHC (Formalin-fixed): 1-2ug/ml for 30 minutes at RT (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH9.0, for 45 minutes at 95 degree C followed by cooling at RT for 20 minutes). Researchers should empirically determine the suitability of the HOMEZ homez for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Homeobox and Leucine Zipper Encoding/HOMEZ, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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