Flow Cytometry (FC/FACS)
(Fig: 1- Cell surface flow analysis of hCD14 in human PBMC using 0.5 ug/10^6 cells. Green represents isotype control; red represents anti-hCD14 antibody (10-4077). Goat anti-mouse PE conjugated secondary antibody was used.)
Mouse anti-Human hCD14 Monoclonal Antibody | anti-hCD14 antibody
NALE Monoclonal Antibody to hCD14 (Clone: RPA-M1) (No Azide Low Endotoxin)
Protein G Chromatography
Protein G Chromatography
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing
Flow Cytometry (FC/FACS)
(Fig: 1- Cell surface flow analysis of hCD14 in human PBMC using 0.5 ug/10^6 cells. Green represents isotype control; red represents anti-hCD14 antibody (10-4077). Goat anti-mouse PE conjugated secondary antibody was used.)
Flow Cytometry (FC/FACS)
(Fig: 1- Cell surface flow analysis of hCD14 in human PBMC using 0.5 ug/10^6 cells. Green represents isotype control; red represents anti-hCD14 antibody (10-4077). Goat anti-mouse PE conjugated secondary antibody was used.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]
Uniprot Description
Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL- (PubMed:23880187).
Research Articles on hCD14
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Product Notes
The hCD14 cd14 (Catalog #AAA668981) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NALE Monoclonal Antibody to hCD14 (Clone: RPA-M1) (No Azide Low Endotoxin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's hCD14 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC/FACS analysis: 0.5-1 ug/10^6 cells. Researchers should empirically determine the suitability of the hCD14 cd14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hCD14, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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