Rabbit anti-Human, Mouse RFX6 Polyclonal Antibody | anti-RFX6 antibody

RFX6 Polyclonal Antibody

Cat. Num. AAA2562682

• Gene Names: RFX6; MTFS; MTCHRS; RFXDC1; dJ955L16.1
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: RFX6; Polyclonal Antibody; RFX6 Polyclonal Antibody; DNA binding protein RFX6; Regulatory factor X domain containing protein 1; RFX6 regulatory factor X; 6; anti-RFX6 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.84mg/mL (varies by lot)
• Sequence Length: 928

• Applicable Applications for anti-RFX6 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:40-1:200; ELISA: 1:5000-1:10000
• Immunogen: Fusion protein of human RFX6
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RFX6 Polyclonal Antibody at dilution of 1:50(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RFX6 Polyclonal Antibody at dilution of 1:50(×200))

Related Product Information for anti-RFX6 antibody

The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.

Product Categories/Family for anti-RFX6 antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 258547126
• NCBI GeneID: 222546
• NCBI Accession #: NP_775831.2; BC039248
• NCBI GenBank Nucleotide #: NP_775831.2
• UniProt Accession #: Q8HWS3
• NCBI Official Full Name: DNA-binding protein RFX6
• NCBI Official Synonym Full Names: regulatory factor X6
• NCBI Official Symbol: RFX6
• NCBI Official Synonym Symbols: MTFS; MTCHRS; RFXDC1; dJ955L16.1
• NCBI Protein Information: DNA-binding protein RFX6
• UniProt Protein Name: DNA-binding protein RFX6
• Protein Family: DNA-binding protein
• UniProt Gene Name: RFX6
• UniProt Synonym Gene Names: RFXDC1
• UniProt Entry Name: RFX6_HUMAN

NCBI Description

The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.[provided by RefSeq, Sep 2010]