Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GUK1 protein (Right) or empty vector (Left) detected with GUK1 antibody)
Mouse GUK1 Monoclonal Antibody | anti-GUK1 antibody
GUK1 antibody
IHC: 1:150
WB: 1:500-2000
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GUK1 protein (Right) or empty vector (Left) detected with GUK1 antibody)
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GUK1 protein (Right) or empty vector (Left) detected with GUK1 antibody)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of GUK1 protein in paraffin embedded Human pancreas tissue using GUK1 antibody)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of GUK1 protein in paraffin embedded Human pancreas tissue using GUK1 antibody)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Uniprot Description
GUK1: Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.4.8; Nucleotide Metabolism - purine; Kinase, other
Chromosomal Location of Human Ortholog: 1q32-q41
Cellular Component: cytosol
Molecular Function: guanylate kinase activity; ATP binding
Biological Process: ATP metabolic process; dATP metabolic process; dGMP metabolic process; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; GDP biosynthetic process; GDP-mannose metabolic process; drug metabolic process; GMP metabolic process; nucleotide phosphorylation; purine nucleotide metabolic process; dGDP biosynthetic process
Research Articles on GUK1
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Product Notes
The GUK1 guk1 (Catalog #AAA533070) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GUK1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Western Blot (WB). FC: 1:100 IHC: 1:150 WB: 1:500-2000. Researchers should empirically determine the suitability of the GUK1 guk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GUK1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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