Rabbit Glucose Transporter GLUT3 Monoclonal Antibody | anti-SLC2A3 antibody
Glucose Transporter GLUT3 Conjugated Antibody
Gene Names
SLC2A3; GLUT3
Reactivity
Human, Mouse, Rat
Applications
Most Applications
Synonyms
Glucose Transporter GLUT3; Monoclonal Antibody; Glucose Transporter GLUT3 Conjugated Antibody; brain antibody; FLJ90380 antibody; Glucose transporter type 3 antibody; Glucose transporter type 3 brain antibody; GLUT 3 antibody; GLUT-3 antibody; GLUT3 antibody; GTR3_HUMAN antibody; Slc2a3 antibody; Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3 antibody; Solute carrier family 2; facilitated glucose transporter member 3 antibody; anti-SLC2A3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-SLC2A3 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-SLC2A3 antibody
Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, Insulin stimulates a rapid and dramatic increase in glucose uptake, largely due to the redistribution of the Insulin-inducible glucose transporter, Glut4. In response to Insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to Insulin. Glut2 expression is seen in pancreatic b cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,924 Da
NCBI Official Full Name
solute carrier family 2, facilitated glucose transporter member 3
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 3
NCBI Official Symbol
SLC2A3
NCBI Official Synonym Symbols
GLUT3
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 3; GLUT-3; glucose transporter type 3, brain
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 3
Protein Family
UniProt Gene Name
SLC2A3
UniProt Synonym Gene Names
GLUT3; GLUT-3
UniProt Entry Name
GTR3_HUMAN
Uniprot Description
GLUT3: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. It???s surface expression is induced by insulin. It is restricted in humans to brain, testis (in the spermatozoa), and skeletal muscle, mostly in triads of slow-twitch fibres. Detected only in the brain of mouse and rat. IHC demonstrates its present in neurons, mainly at the plasma membrane, and to a lesser extent on intracellular vesicles distinct from synaptic vesicles. Present in the a-granules of human platelets, where it is translocated to the cell surface in response to thrombin stimulation. Its surface expression is increased by insulin or insulin growth-factor in cultured L6 muscle cells.
Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: integral to membrane; plasma membrane
Molecular Function: glucose transmembrane transporter activity
Biological Process: vitamin metabolic process; hexose transport; carbohydrate metabolic process; L-ascorbic acid metabolic process; pathogenesis; glucose transport; transmembrane transport; water-soluble vitamin metabolic process
Research Articles on SLC2A3
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Product Notes
The SLC2A3 slc2a3 (Catalog #AAA9457164) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glucose Transporter GLUT3 Conjugated Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Glucose Transporter GLUT3 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the SLC2A3 slc2a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glucose Transporter GLUT3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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