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Western Blot (Western Blot analysis using GGPS1 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GGPS1 protein (Right) or empty vector (Left) detected with GGPS1 antibody)

Mouse GGPS1 Monoclonal Antibody | anti-GGPS1 antibody

GGPS1 antibody

Gene Names
GGPS1; GGPPS; GGPPS1
Applications
Western Blot
Purity
GGPS1 antibody was purified by affinity chromatography.
Synonyms
GGPS1; Monoclonal Antibody; GGPS1 antibody; Monoclonal GGPS1; Anti-GGPS1; Geranylgeranyl Diphosphate Synthase 1; GGPPS; GGPPS1; GGPS 1; GGPS-1; anti-GGPS1 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1C6
Purity/Purification
GGPS1 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
246
Applicable Applications for anti-GGPS1 antibody
Western Blot (WB)
Application Notes
WB: 1:2000
Biological Significance
GGPS1 is a member of the prenyltransferase family with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor.
Cross-Reactivity
Human
Immunogen
GGPS1 antibody was raised in mouse using a full length recombinant protein of human GGPS1 (NP_004828) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot

(Western Blot analysis using GGPS1 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GGPS1 protein (Right) or empty vector (Left) detected with GGPS1 antibody)

Western Blot (Western Blot analysis using GGPS1 antibodyWestern Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant GGPS1 protein (Right) or empty vector (Left) detected with GGPS1 antibody)
Related Product Information for anti-GGPS1 antibody
Mouse monoclonal GGPS1 antibody
Product Categories/Family for anti-GGPS1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,423 Da
NCBI Official Synonym Full Names
geranylgeranyl diphosphate synthase 1
NCBI Official Symbol
GGPS1
NCBI Official Synonym Symbols
GGPPS; GGPPS1
NCBI Protein Information
geranylgeranyl pyrophosphate synthase
UniProt Protein Name
Geranylgeranyl pyrophosphate synthase
UniProt Gene Name
GGPS1
UniProt Synonym Gene Names
GGPP synthase; GGPPSase
UniProt Entry Name
GGPPS_HUMAN

NCBI Description

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]

Uniprot Description

GGPS1: Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Belongs to the FPP/GGPP synthase family.

Protein type: EC 2.5.1.10; EC 2.5.1.29; Motility/polarity/chemotaxis; Transferase; EC 2.5.1.1; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: cytosol

Molecular Function: geranyltranstransferase activity; dimethylallyltranstransferase activity; farnesyltranstransferase activity; metal ion binding

Biological Process: isoprenoid metabolic process; geranylgeranyl diphosphate biosynthetic process; geranyl diphosphate biosynthetic process; farnesyl diphosphate biosynthetic process; cholesterol biosynthetic process

Research Articles on GGPS1

Similar Products

Product Notes

The GGPS1 ggps1 (Catalog #AAA533824) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GGPS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the GGPS1 ggps1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GGPS1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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