Western Blot (WB)
(Western Blot detection of KIF11 in MCF7, 293T&Hela cell lysates using KIF11 antibody (1:1000 diluted).)
Mouse anti-Human Eg5/KIF11 Monoclonal Antibody | anti-Eg5 antibody
Eg5/KIF11 Monoclonal Antibody
ICC: 1:200
IP: 1:50-1:200
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot detection of KIF11 in MCF7, 293T&Hela cell lysates using KIF11 antibody (1:1000 diluted).)
Western Blot (WB)
(Western Blot detection of KIF11 in MCF7, 293T&Hela cell lysates using KIF11 antibody (1:1000 diluted).)
Immunocytochemistry (ICC)
(Immunocytochemistry stain of Hela using KIF11 antibody (1:200).)
Immunocytochemistry (ICC)
(Immunocytochemistry stain of Hela using KIF11 antibody (1:200).)
Immunoprecipitation (IP)
(Immunoprecipitation analysis of Jurkat cell lysates using KIF11 antibody)
Immunoprecipitation (IP)
(Immunoprecipitation analysis of Jurkat cell lysates using KIF11 antibody)
NCBI and Uniprot Product Information
Observed Band Size: 130KDa
Additional band size: 75K
NCBI Description
This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008]
Uniprot Description
KIF11: a cytoskeletal protein that belongs to the kinesin-like protein family. BimC subfamily. Interacts with the thyroid hormone receptor in the presence of thyroid hormone. Plays a role in chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. Phosphorylation regulates its association with the spindle apparatus.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 10q24.1
Cellular Component: spindle pole; kinesin complex; microtubule; membrane; spindle microtubule; cytoplasm; spindle; cytosol
Molecular Function: plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; protein complex binding; microtubule motor activity; protein kinase binding; ATP binding
Biological Process: mitosis; mitotic spindle organization and biogenesis; mitotic centrosome separation; cell division; metabolic process; regulation of mitotic centrosome separation; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; spindle organization and biogenesis; microtubule-based movement; chromosome segregation
Disease: Microcephaly With Or Without Chorioretinopathy, Lymphedema, Or Mental Retardation
Research Articles on Eg5
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Product Notes
The Eg5 kif11 (Catalog #AAA3014221) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Eg5/KIF11 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Eg5/KIF11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 1:1000 ICC: 1:200 IP: 1:50-1:200. Researchers should empirically determine the suitability of the Eg5 kif11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Eg5/KIF11, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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