Western Blot (WB)
(Western blot analysis using Dynamin1 mouse mAb against C6 (1), NIH/3T3 (2), SKN-SH (3), LN18 (4), SHSY5Y (5) cell lysate and rat brain tiisues lysate (6).)
Mouse anti-Human Dynamin-1 Monoclonal Antibody | anti-DNM1 antibody
Anti-Dynamin-1 Mouse mAb
Western Blot (WB)
(Western blot analysis using Dynamin1 mouse mAb against C6 (1), NIH/3T3 (2), SKN-SH (3), LN18 (4), SHSY5Y (5) cell lysate and rat brain tiisues lysate (6).)
Western Blot (WB)
(Western blot analysis using Dynamin1 mouse mAb against C6 (1), NIH/3T3 (2), SKN-SH (3), LN18 (4), SHSY5Y (5) cell lysate and rat brain tiisues lysate (6).)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lymph tissue (A), glioma tissue (B) and cerebellum tissue (C), showing membrane localization using Dynamin1 mouse mAb with DAB staining)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lymph tissue (A), glioma tissue (B) and cerebellum tissue (C), showing membrane localization using Dynamin1 mouse mAb with DAB staining)
NCBI and Uniprot Product Information
NCBI Description
mediates GTP hydrolysis; plays a role in receptor mediated endocytosis; required for agonist-induced internalization of the epidermal growth factor receptor [RGD, Feb 2006]
Uniprot Description
DYN1: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within the presynaptic compartment and may participate in specialized neuronal functions such as rapid synaptic vesicle recycling. Part of a protein network that controls nucleation of actin from membranes. Contains one PH domain.
Protein type: EC 3.6.5.5; Hydrolase; Microtubule-binding; Motility/polarity/chemotaxis; Motor; Vesicle
Chromosomal Location of Human Ortholog: 3p12
Cellular Component: cytoplasm; Golgi apparatus; membrane coat; mitochondrial membrane; myelin sheath; photoreceptor inner segment; plasma membrane; protein complex; synapse; synaptic vesicle
Molecular Function: D2 dopamine receptor binding; GTPase activity; identical protein binding; microtubule binding; nitric-oxide synthase binding; protein binding; protein C-terminus binding; protein complex binding; protein dimerization activity; protein kinase binding
Biological Process: adult locomotory behavior; endocytosis; endosome organization and biogenesis; G-protein coupled receptor internalization; mitochondrial fission; protein tetramerization; receptor internalization; receptor-mediated endocytosis; sensory perception of sound; synaptic transmission, GABAergic
Research Articles on DNM1
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Product Notes
The DNM1 dnm1 (Catalog #AAA475691) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Dynamin-1 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Dynamin-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DNM1 dnm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dynamin-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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