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Mouse DMPO Monoclonal Antibody | anti-DMPO antibody

DMPO monoclonal antibody (1)

Reactivity
General
Does not cross-react with non-adducted proteins or DNA.
Does not cross-react with ovalbumin
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Protein G affinity purified
Synonyms
DMPO; Monoclonal Antibody; DMPO monoclonal antibody (1); anti-DMPO antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
General
Does not cross-react with non-adducted proteins or DNA.
Does not cross-react with ovalbumin
Clonality
Monoclonal
Isotype
IgG
Clone Number
1
Specificity
Recognizes DMPO, DMPO-octanoic acid, DMPO-protein adducts and DMPO-DNA adducts
Purity/Purification
Protein G affinity purified
Form/Format
Liquid. In PBS, pH7.4, containing 10% glycerol and 0.02% sodium azide
Applicable Applications for anti-DMPO antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Source Note
Hybridoma tissue culture supernatant
Immunogen
DMPO-octanoic acid conjugated to ovalbumin
Preparation and Storage
For long term storage, store at 4 degree C. Dilute only prior to immediate use
Shipping: Shipped on Blue Ice
Related Product Information for anti-DMPO antibody
Oxidative stress resulting in the formation of biological radicals has been implicated in a number of human diseases, such as cancer and aging. There is, however, a paucity of reliable methods for in vivo or ex vivo detection of radical formation. Until now the only general technique that allowed for the detection of these highly reactive species was electron spin resonance (ESR) using spin traps. One of the most popular of these spin traps is 5,5-dimethyl-1-pyrroline N-oxide (DMPO). In the ESR method, radicals are trapped by DMPO, and the DMPO spin adduct signal is measured quantitatively by an ESR spectrometer. The DMPO, mAb (1) specifically reacts with DMPO-protein and DMPO-DNA adducts and therefore highly simplifies the detection of radical formation compared to the ESR method.

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Product Notes

The DMPO (Catalog #AAA566291) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DMPO monoclonal antibody (1) reacts with General Does not cross-react with non-adducted proteins or DNA. Does not cross-react with ovalbumin and may cross-react with other species as described in the data sheet. AAA Biotech's DMPO can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the DMPO for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DMPO, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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