SDS-PAGE
CHO cells anti-Homo sapiens Daratumumab Monoclonal Antibody
Daratumumab
Reactivity
Homo sapiens
Purity
>95%
Synonyms
Daratumumab; Monoclonal Antibody; HuMax-CD38; CD38; anti-Daratumumab antibody
Host
CHO cells
Reactivity
Homo sapiens
Clonality
Monoclonal
Isotype
IgG1-kappa
Specificity
Specificity target name;species CD38[Homo sapiens]
Purity/Purification
>95%
Form/Format
PBS buffer PH7.5
Concentration
1mg/ml (varies by lot)
CAS Number
945721-28-8
Activity in vitro
Daratumumab was studied in a series of in vitro assays and was found to induce
CDC in freshly isolated MM cells obtained from the bone marrow of 13 previously
untreated or relapsed MM patients. Furthermore, daratumumab triggered antibodydependent
cell-mediated cytotoxicity (ADCC) in CD38-expressing MM cell lines in
peripheral blood mononuclear cells (PBMCs) enriched for NK cells, as well as in
patient MM cells in the presence of both autologous and allogeneic effector cells.
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
SDS-PAGE
SDS-PAGE
Related Product Information for anti-Daratumumab antibody
Daratumumab is a human monoclonal antibody that targets CD38, a cell surface
protein that is overexpressed on multiple myeloma (MM) cells.
Product Categories/Family for anti-Daratumumab antibody
Similar Products
Product Notes
The Daratumumab (Catalog #AAA156244) is an Antibody produced from CHO cells and is intended for research purposes only. The product is available for immediate purchase. The Daratumumab reacts with Homo sapiens and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Daratumumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
