Mouse CDK4 Monoclonal Antibody | anti-CDK4 antibody
CDK4, p34 (CDK4, Cyclin-dependent Kinase 4, p34CDK4) (BSA & Azide Free) (APC)
Reactivity
Human, Mouse, Porcine, Rat
Applications
Immunofluorescence, Immunoprecipitation, Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
CDK4; Monoclonal Antibody; p34 (CDK4; Cyclin-dependent Kinase 4; p34CDK4) (BSA & Azide Free) (APC); anti-CDK4 antibody
Host
Mouse
Reactivity
Human, Mouse, Porcine, Rat
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
0.N.199
Specificity
Recognizes p34 (34kD). Does not crossreact with other cdks. Species Crossreactivity: Human, mouse, rat and porcine.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-CDK4 antibody
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
Immunogen
Purified recombinant cdk4 protein. Cellular Localization: Nuclear and cyotplasmic. Epitope: aa1-20.
Conjugate
APC
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-CDK4 antibody
References
1. Altucci L; Addeo R; Cicatiello L; Dauvois S; Parker MG; Truss M; Beato M; Sica V; Bresciani F; Weisz A. 17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells. Oncogene, 1996 Jun 6, 12(11):2315-24. 2. Beauchamp RD; Sheng HM; Shao JY; Thompson EA; Ko TC. Intestinal cell cycle regulations. Interactions of cyclin D1, Cdk4, and p21Cip1. Annals of Surgery, 1996 May, 223(5):620-7; discussion 627-8. 3. Carlson BA; Dubay MM; Sausville EA; Brizuela L; Worland PJ. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Research, 1996 Jul 1, 56(13):2473-8. 4. Dai K; Kobayashi R; Beach D. Physical interaction of mammalian CDC37 with CDK4. Journal of Biological Chemistry, 1996 Sep 6, 271(36):22030-4. 5. Dobashi Y; Kudoh T; Toyoshima K; Akiyama T. Persistent activation of CDK4 during neuronal differentiation of rat pheochromocytoma PC12 cells. Biochemical and Biophysical Research Communications, 1996 Apr 16, 221(2):351-5. 6. Ewen ME. p53-dependent repression of cdk4 synthesis in transforming growth factor-beta-induced G1 cell cycle arrest. Journal of Laboratory and Clinical Medicine, 1996 Oct, 128(4):355-60. 7. Foster JS; Wimalasena J. Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells. Molecular Endocrinology, 1996 May, 10(5):488-98. 8. Garcia-Conde J; Cabanillas F. Mantle cell lymphoma: a lymphoproliferative disorder associated with aberrant function of the cell cycle. Leukemia, 1996 Jun, 10 Suppl 2:s78-83. 9. Guan KL; Jenkins CW; Li Y; O'Keefe CL; Noh S; Wu X; Zariwala M; Matera AG; Xiong Y. Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4. Molecular Biology of the Cell, 1996 Jan, 7(1):57-70. 10. Ichimura K; Schmidt EE; Goike HM; Collins VP. Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene. Oncogene, 1996 Sep 5, 13(5):1065-72.
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Product Notes
The CDK4 (Catalog #AAA6265986) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CDK4, p34 (CDK4, Cyclin-dependent Kinase 4, p34CDK4) (BSA & Azide Free) (APC) reacts with Human, Mouse, Porcine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDK4 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the CDK4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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