Testing Data
(Staining of stimulated rat spleen cells with Mouse anti Rat CD54:Alexa Fluor 488 (MBS213153A488))
Mouse CD54 Monoclonal Antibody | anti-CD54 antibody
MOUSE ANTI RAT CD54
Purified IgG - liquid
Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/50
Immunohistology - Paraffin: Application Note: This clone is suitable for use on paraffin embedded material using target unmasking fluid.
Preparation
Fusion Partners
Shelf Life: 18 months from date of despatch.
Testing Data
(Staining of stimulated rat spleen cells with Mouse anti Rat CD54:Alexa Fluor 488 (MBS213153A488))
Testing Data
(Staining of stimulated rat spleen cells with Mouse anti Rat CD54:Alexa Fluor 488 (MBS213153A488))
Testing Data
(Staining of stimulated rat spleen cells with Mouse anti Rat CD54:FITC (MBS211098))
Testing Data
(Staining of stimulated rat spleen cells with Mouse anti Rat CD54:FITC (MBS211098))
Testing Data
(Staining of frozen rat spleen with Mouse anti Rat CD54 (MBS213153))
Testing Data
(Staining of frozen rat spleen with Mouse anti Rat CD54 (MBS213153))
NCBI and Uniprot Product Information
NCBI Description
cell adhesion molecule; ligand for leukocyte adhesion molecule LFA-1 [RGD, Feb 2006]
Uniprot Description
ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta.
Protein type: Immunoglobulin superfamily; Cell adhesion; Membrane protein, integral
Cellular Component: extracellular space; cell surface; focal adhesion; membrane; integral to plasma membrane; plasma membrane; immunological synapse; lipid raft; external side of plasma membrane
Molecular Function: integrin binding; protein complex binding
Biological Process: positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; response to lipopolysaccharide; response to organic cyclic substance; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; cellular response to nutrient levels; leukocyte adhesion; cell-cell adhesion; sensory perception of sound; ovarian follicle development; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; membrane to membrane docking; response to sulfur dioxide; cell adhesion; acute inflammatory response to antigenic stimulus; response to drug; regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; response to amphetamine; cell aging; response to amino acid stimulus; positive regulation of peptidyl-tyrosine phosphorylation; response to ethanol; response to copper ion; positive regulation of actin filament polymerization; positive regulation of vasoconstriction; response to hypoxia; adhesion to host; cell adhesion mediated by integrin; response to ionizing radiation; leukocyte migration; positive regulation of GTPase activity
Research Articles on CD54
Similar Products
Product Notes
The CD54 icam1 (Catalog #AAA213154) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD54 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistology Paraffin*. Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/25; Maximum Dilution: 1/50 Immunohistology - Paraffin: Application Note: This clone is suitable for use on paraffin embedded material using target unmasking fluid. Researchers should empirically determine the suitability of the CD54 icam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD54, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
