Western Blot (WB)
(Western blot analysis of CANT1 expression in Jurkat cell line lysates, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse CANT1 Polyclonal Antibody | anti-CANT1 antibody
CANT1 Antibody
Gene Names
CANT1; DBQD; EDM7; DBQD1; SCAN1; SHAPY; SCAN-1
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CANT1; Polyclonal Antibody; CANT1 Antibody; Apyrase; Apyrase homolog; Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase; Calcium activated nucleotidase 1; CANT 1; CANT1_HUMAN; Putative MAPK activating protein PM09; Putative MAPK-activating protein PM09; Putative NF kappa B activating protein 107; Putative NF-kappa-B-activating protein 107; SCAN 1; SCAN-1; SHAPY; Soluble Ca activated nucleotidase isozyme 1; Soluble calcium activated nucleotidase 1; Soluble calcium activated nucleotidase SCAN 1; Soluble calcium-activated nucleotidase 1; anti-CANT1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
CANT1 antibody detects endogenous levels of total CANT1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
401
Applicable Applications for anti-CANT1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Endoplasmic Reticulum Membrane. Golgi Apparatus > Golgi Stack Membrane. Processed form: Secreted.
Tissue Specificity
Widely expressed.
Predicted Cross Reactivity
Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
Similarity
Pig (90%), Bovine (90%), Horse (90%), Rabbit (90%), Dog (90%), Chicken (100%), Xenopus (90%)
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of CANT1 expression in Jurkat cell line lysates, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of CANT1 expression in Jurkat cell line lysates, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-CANT1 antibody
Function: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP (PubMed:12234496, PubMed:15248776, PubMed:15006348, PubMed:16835225). Involved in proteoglycan synthesis (PubMed:22539336).
Subunit Structure: Monomer (PubMed:12234496, PubMed:15006348). Homodimer; dimerization is Ca2+-dependent (PubMed:16835225). Homodimer; disulfide-linked (membrane form) (PubMed:16835225).
Post-translational Modifications: N-glycosylated.
Similarity: Belongs to the apyrase family.
Subunit Structure: Monomer (PubMed:12234496, PubMed:15006348). Homodimer; dimerization is Ca2+-dependent (PubMed:16835225). Homodimer; disulfide-linked (membrane form) (PubMed:16835225).
Post-translational Modifications: N-glycosylated.
Similarity: Belongs to the apyrase family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 45 kDa
Predicted: 45 kDa
Predicted: 45 kDa
NCBI Official Full Name
soluble calcium-activated nucleotidase 1
NCBI Official Synonym Full Names
calcium activated nucleotidase 1
NCBI Official Symbol
CANT1
NCBI Official Synonym Symbols
DBQD; EDM7; DBQD1; SCAN1; SHAPY; SCAN-1
NCBI Protein Information
soluble calcium-activated nucleotidase 1
UniProt Protein Name
Soluble calcium-activated nucleotidase 1
Protein Family
UniProt Gene Name
CANT1
UniProt Synonym Gene Names
SHAPY; SCAN-1
NCBI Description
This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010]
Uniprot Description
Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP (PubMed:12234496, PubMed:15248776, PubMed:15006348, PubMed:16835225). Involved in proteoglycan synthesis (PubMed:22539336).
Research Articles on CANT1
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Product Notes
The CANT1 cant1 (Catalog #AAA9604104) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CANT1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CANT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CANT1 cant1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CANT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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