Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant C17orf37 protein (Right) or empty vector (Left) detected with C17orf37 antibody)
Mouse C17orf37 Monoclonal Antibody | anti-C17orf37 antibody
C17orf37 antibody
Gene Names
MIEN1; C35; ORB3; XTP4; RDX12; C17orf37
Applications
Western Blot
Purity
C17orf37 antibody was purified by affinity chromatography.
Synonyms
C17orf37; Monoclonal Antibody; C17orf37 antibody; Monoclonal C17orf37; Anti-C17orf37; C35; MGC14832; ORB3; RDX12; XTP4; Corf37 17; Corf37-17; anti-C17orf37 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1G2
Purity/Purification
C17orf37 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
0.5-1 mg/ml (varies by lot)
Sequence Length
207
Applicable Applications for anti-C17orf37 antibody
Western Blot (WB)
Application Notes
WB: 1:500
Biological Significance
May be involved in a redox-related process (Potential). May act as a signaling protein that increases migratory potential and invasiveness of cancer cells by enhancing NF-kappa-B activation mediated by AKT1, hence the transcription of downstream genes such as MMP9, VEGF and PLAU.
Cross-Reactivity
Human
Immunogen
C17orf37 antibody was raised in Mouse using full length human recombinant protein of human C17orf37 produced in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant C17orf37 protein (Right) or empty vector (Left) detected with C17orf37 antibody)
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant C17orf37 protein (Right) or empty vector (Left) detected with C17orf37 antibody)
Related Product Information for anti-C17orf37 antibody
Mouse monoclonal C17orf37 antibody
Product Categories/Family for anti-C17orf37 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
12,403 Da
NCBI Official Full Name
chromosome 17 open reading frame 37, isoform CRA_b
NCBI Official Synonym Full Names
migration and invasion enhancer 1
NCBI Official Symbol
MIEN1
NCBI Official Synonym Symbols
C35; ORB3; XTP4; RDX12; C17orf37
NCBI Protein Information
migration and invasion enhancer 1
UniProt Protein Name
Migration and invasion enhancer 1
UniProt Gene Name
MIEN1
UniProt Synonym Gene Names
C17orf37; RDX12; XTP4
UniProt Entry Name
MIEN1_HUMAN
Uniprot Description
MIEN1: Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. Belongs to the SelWTH family.
Chromosomal Location of Human Ortholog: 17q12
Cellular Component: nucleoplasm; cytoplasm; cytosol
Molecular Function: selenium binding
Biological Process: positive regulation of filopodium formation; apoptosis; cell redox homeostasis; negative regulation of apoptosis; positive regulation of cell migration
Research Articles on C17orf37
Similar Products
Product Notes
The C17orf37 mien1 (Catalog #AAA833274) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's C17orf37 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500. Researchers should empirically determine the suitability of the C17orf37 mien1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C17orf37, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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