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Mouse Bacillus anthracis Protective Antigen Monoclonal Antibody

Bacillus anthracis Protective Antigen Monoclonal Antibody

Applications
ELISA, Immunoblot, Western Blot
Synonyms
Bacillus anthracis Protective Antigen; Monoclonal Antibody; Bacillus anthracis Protective Antigen Monoclonal Antibody; anti-Bacillus anthracis Protective Antigen antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
Bacillus anthracis Protective Antigen [These monoclonal antibodies recognize different epitopes of the 83kD and 63kD forms of B. anthracis Protective Antigen. They do not cross-react with B. anthracis Edema Factor, Lethal Factor, or spore/vegetative surface antigens.]
These antibodies recognize different epitopes of the 83kD and 63 kD forms of B. anthracis PA. They do not crossreact with B. anthracis EF, LF, or spore/vegetative surface antigens.
Form/Format
200 ug purified antibody in PBS, pH 7.4.
Applicable Applications for anti-Bacillus anthracis Protective Antigen antibody
ELISA, Immunoblot
Application Notes
Immunoblotting: use 18721, 18723, 18725, or 18726 at 5 ug/ml.
Sandwich ELISA: use coating antibody (18720 or 18725) at 5 ug/ml; use detect antibody (18722, 18723, or18726) at 1 ug/ml.
Antigen
Purified B. anthracis Protective Antigen (83 kD).
Preservatives
0.1% NaN3
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
These antibodies are stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-Bacillus anthracis Protective Antigen antibody
Anthrax toxin produced by Bacillus anthracis is composed of three proteins: Protective Antigen (PA), Edema Factor (EF), and Lethal Factor (LF). Toxicity requires the assembly of all three of these proteins, and this process is initiated when full-length PA binds to the cell surface ATR (anthrax toxin receptor). After binding, PA is enzymatically cleaved to yield a 63 kD fragment which then binds EF and LF, and the complex is internalized.
Product Categories/Family for anti-Bacillus anthracis Protective Antigen antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
Bacillus anthracis protective antigen

Similar Products

Product Notes

The Bacillus anthracis Protective Antigen (Catalog #AAA190061) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Bacillus anthracis Protective Antigen can be used in a range of immunoassay formats including, but not limited to, ELISA, Immunoblot. Immunoblotting: use 18721, 18723, 18725, or 18726 at 5 ug/ml. Sandwich ELISA: use coating antibody (18720 or 18725) at 5 ug/ml; use detect antibody (18722, 18723, or18726) at 1 ug/ml. Researchers should empirically determine the suitability of the Bacillus anthracis Protective Antigen for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bacillus anthracis Protective Antigen, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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