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Testing Data (Fig-1: Expression analysis of Delta like 3. Anti-Delta like 3 antibody (11-10038) was used at 2 ug/ml on A375 lysate.)

Rabbit Delta like 3 Polyclonal Antibody | anti-DLL3 antibody

Polyclonal Antibody to Delta like 3

Gene Names
DLL3; SCDO1
Reactivity
Human
Predicted: Rat
Applications
Western Blot
Purity
Purified
Protein A Chromatography
Synonyms
Delta like 3; Polyclonal Antibody; Polyclonal Antibody to Delta like 3; DLL3; Drosophila Delta homolog 3; Antibody to Delta like 3; Anti-Delta like 3 Antibody; Delta like 3 Antibody; anti-DLL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified
Protein A Chromatography
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
618
Applicable Applications for anti-DLL3 antibody
Western Blot (WB)
Application Notes
WB: 2-4 ug/ml
Immunogen Information
A partial length recombinant Delta like 3 protein (amino acids 62-286) was used as the immunogen for this antibody.
Antigen
Delta like 3
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.

Testing Data

(Fig-1: Expression analysis of Delta like 3. Anti-Delta like 3 antibody (11-10038) was used at 2 ug/ml on A375 lysate.)

Testing Data (Fig-1: Expression analysis of Delta like 3. Anti-Delta like 3 antibody (11-10038) was used at 2 ug/ml on A375 lysate.)
Related Product Information for anti-DLL3 antibody
Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation.
Product Categories/Family for anti-DLL3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
61,178 Da
NCBI Official Full Name
Delta-like protein 3
NCBI Official Synonym Full Names
delta like canonical Notch ligand 3
NCBI Official Symbol
DLL3
NCBI Official Synonym Symbols
SCDO1
NCBI Protein Information
delta-like protein 3
UniProt Protein Name
Delta-like protein 3
Protein Family
UniProt Gene Name
DLL3
UniProt Synonym Gene Names
Delta3

NCBI Description

This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

DLL3: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Can bind and activate Notch-1 or another Notch receptor.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.2

Biological Process: skeletal development

Disease: Spondylocostal Dysostosis 1, Autosomal Recessive

Research Articles on DLL3

Similar Products

Product Notes

The DLL3 dll3 (Catalog #AAA668623) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Delta like 3 reacts with Human Predicted: Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Delta like 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 2-4 ug/ml. Researchers should empirically determine the suitability of the DLL3 dll3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Delta like 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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