Mouse anti-Human ASF1 Anti-Silencing Function 1 Homolog B Monoclonal Antibody | anti-ASF1B antibody
Mouse Anti Human ASF1 Anti-Silencing Function 1 Homolog B
Gene Names
ASF1B; CIA-II
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified from mouse ascitic fluids by protein-A affinity chromatography
Synonyms
ASF1 Anti-Silencing Function 1 Homolog B; Monoclonal Antibody; Mouse Anti Human ASF1 Anti-Silencing Function 1 Homolog B; ASF1B Antibody; Mouse Anti Human; Histone chaperone ASF1B; Anti-silencing function protein 1 homolog B; hAsf1; hAsf1b; CCG1-interacting factor A-II; CIA-II; hCIA-II; ASF1B; anti-ASF1B antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
PAT1D4AT
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Form/Format
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence Length
202
Applicable Applications for anti-ASF1B antibody
ELISA (EIA), Western Blot (WB)
Application Notes
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity.
Ig Subclass
Mouse IgG2b heavy chain and k light chain.
Immunogen
Anti-human ASF1B mAb, clone PAT1D4AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ASF1B protein (1-202 amino acids) purified from E Coli.
Preparation and Storage
Storage: For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-ASF1B antibody
ASF1 Anti-Silencing Function 1 Homolog B (ASF1B) belongs to the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 protein in yeast. ASF1B is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may have a crucial role in modulating the nucleosome structure of chromatin by guaranteeing a regular supply of histones at sites of nucleosome assembly. ASF1B cooperates with CAF-1 (chromatin assembly factor 1) to stimulate replication-dependent chromatin assembly. ASF1B is highly expressed in the testis and at lower levels in colon, small intestine and thymus. ASF1B is necessary for spermatogenesis.
Product Categories/Family for anti-ASF1B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,434 Da
NCBI Official Full Name
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
NCBI Official Synonym Full Names
anti-silencing function 1B histone chaperone
NCBI Official Symbol
ASF1B
NCBI Official Synonym Symbols
CIA-II
NCBI Protein Information
histone chaperone ASF1B
UniProt Protein Name
Histone chaperone ASF1B
Protein Family
UniProt Gene Name
ASF1B
UniProt Synonym Gene Names
hAsf1; hAsf1b; CIA-II; hCIA-II
UniProt Entry Name
ASF1B_HUMAN
Uniprot Description
ASF1B: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis. Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with HAT1, NASP, TAF1, TLK1 and TLK2. Highly expressed in testis and at lower levels in colon, small intestine and thymus. Belongs to the ASF1 family.
Chromosomal Location of Human Ortholog: 19p13.12
Cellular Component: nuclear chromatin; nucleoplasm; protein complex
Molecular Function: protein binding
Biological Process: DNA replication-dependent nucleosome assembly; DNA replication-independent nucleosome assembly
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Product Notes
The ASF1B asf1b (Catalog #AAA140533) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human ASF1 Anti-Silencing Function 1 Homolog B reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ASF1 Anti-Silencing Function 1 Homolog B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Researchers should empirically determine the suitability of the ASF1B asf1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASF1 Anti-Silencing Function 1 Homolog B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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