Testing Data
Mouse anti-Human ARHI Monoclonal Antibody | anti-ARHI antibody
Anti-ARHI Antibody
Reactivity
Human
Applications
ELISA, Western Blot, Immunoprecipitation
Purity
Affinity purified
Synonyms
ARHI; Monoclonal Antibody; Anti-ARHI Antibody; Anti-ARHI Mouse Monoclonal Antibody; anti-ARHI antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
229
Applicable Applications for anti-ARHI antibody
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP)
Application Notes
ELISA: 1/2000 - 1/5000
Immunoprecipitation: Use at an assay dependent dilution
Western Blot: 1/1000
Immunoprecipitation: Use at an assay dependent dilution
Western Blot: 1/1000
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Immunogen
Recombinant full length ARHI protein (Human)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Testing Data
Testing Data
Related Product Information for anti-ARHI antibody
ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane localization motif. ARHI mRNA is detected in all normal breast and ovarian epithelial cell cultures tested, as well as in normal ovary, heart, liver, pancreas and brain however ARHI expression is down-regulated in breast and ovarian tumors. Reactivation of ARHI expression in breast cancer cells is associated with increased histone H3 acetylation and decreased lysine 9 methylation of histone H3.
NCBI and Uniprot Product Information
Uniprot Description
DIRAS3: a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq, Oct 2010]
Protein type: G protein, monomeric; G protein; G protein, monomeric, di-Ras
Chromosomal Location of Human Ortholog: 1p31
Cellular Component: plasma membrane
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: genetic imprinting; small GTPase mediated signal transduction; regulation of cyclin-dependent protein kinase activity
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Product Notes
The ARHI diras3 (Catalog #AAA415082) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-ARHI Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ARHI can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP). ELISA: 1/2000 - 1/5000 Immunoprecipitation: Use at an assay dependent dilution Western Blot: 1/1000. Researchers should empirically determine the suitability of the ARHI diras3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHI, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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