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Mouse alphaB Crystallin Monoclonal Antibody | anti-CRYAB antibody

alphaB Crystallin monoclonal antibody (1B6.1 3G4)

Reactivity
Human, Mouse, Rat, Chicken, Bovine
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Protein G affinity purified
Synonyms
alphaB Crystallin; Monoclonal Antibody; alphaB Crystallin monoclonal antibody (1B6.1 3G4); anti-CRYAB antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat, Chicken, Bovine
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1B6.1-3G4
Purity/Purification
Protein G affinity purified
Form/Format
Liquid. In PBS, pH7.2, containing 50% glycerol and 0.09% sodium azide
Applicable Applications for anti-CRYAB antibody
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Source Note
Purified from hybridoma tissue culture supernatant
Immunogen
Bovine alphaB-crystallin
Preparation and Storage
For long term storage, store at -20 degree C. Avoid freeze/thaw cycles
Shipping: Shipped on Blue Ice
Related Product Information for anti-CRYAB antibody
Alpha-crystallins, which are part of the small Heat shock family members, are major water-soluble proteins present in the lens of the mammalian eye. Phosphorylation of serine residues which occurs during development and in response to stress, is intimately linked with its function. Chaperone activity requires, and is modulated by, oligomerization and is limited to binding unfolded intermediates to prevent irreversible aggregation.
Product Categories/Family for anti-CRYAB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
20,037 Da
NCBI Official Full Name
Alpha-crystallin B chain
NCBI Official Symbol
CRYAB
NCBI Protein Information
alpha-crystallin B chain
UniProt Protein Name
Alpha-crystallin B chain
Protein Family
UniProt Gene Name
CRYAB
UniProt Synonym Gene Names
CRYA2
UniProt Entry Name
CRYAB_BOVIN

Uniprot Description

CRYAB: a major structural protein of the eye lens. A member of the small heat shock protein (sHSP also known as the HSP20) family. Alpha-B is expressed in the lens as well as other tissues. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.

Protein type: Heat shock protein; Chaperone

Cellular Component: cytoplasm; cytosol; mitochondrion; myelin sheath; nucleus; plasma membrane; Z disc

Molecular Function: metal ion binding; protein homodimerization activity; structural constituent of eye lens; unfolded protein binding

Biological Process: lens development in camera-type eye; muscle development; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of intracellular transport; protein homooligomerization; response to hydrogen peroxide; response to hypoxia; tubulin folding

Research Articles on CRYAB

Similar Products

Product Notes

The CRYAB cryab (Catalog #AAA567149) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The alphaB Crystallin monoclonal antibody (1B6.1 3G4) reacts with Human, Mouse, Rat, Chicken, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's alphaB Crystallin can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). Researchers should empirically determine the suitability of the CRYAB cryab for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "alphaB Crystallin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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