Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blotAll lanes: PRPF4 antibody at 3.89 ug/mlLane 1: Jurkat whole cell lysateLane 2: Hela whole cell lysateLane 3: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 58 kDaObserved band size: 58 kDa)

Rabbit anti-Human PRPF4 Polyclonal Antibody | anti-PRPF4 antibody

PRPF4 Antibody

Gene Names
PRPF4; PRP4; RP70; HPRP4; Prp4p; HPRP4P; SNRNP60
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
PRPF4; Polyclonal Antibody; PRPF4 Antibody; U4/U6 small nuclear ribonucleoprotein Prp4; PRP4 homolog; hPrp4; U4/U6 snRNP 60 kDa protein; WD splicing factor Prp4; PRP4; anti-PRPF4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
521
Applicable Applications for anti-PRPF4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human U4/U6 small nuclear ribonucleoprotein Prp4 protein (N-260AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-163263 / sc-163264
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: PRPF4 antibody at 3.89 ug/mlLane 1: Jurkat whole cell lysateLane 2: Hela whole cell lysateLane 3: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 58 kDaObserved band size: 58 kDa)

Western Blot (WB) (Western blotAll lanes: PRPF4 antibody at 3.89 ug/mlLane 1: Jurkat whole cell lysateLane 2: Hela whole cell lysateLane 3: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 58 kDaObserved band size: 58 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7045737 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7045737 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045737 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045737 at dilution of 1:100)
Related Product Information for anti-PRPF4 antibody
Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58,321 Da
NCBI Official Full Name
U4/U6 small nuclear ribonucleoprotein Prp4 isoform 2
NCBI Official Synonym Full Names
pre-mRNA processing factor 4
NCBI Official Symbol
PRPF4
NCBI Official Synonym Symbols
PRP4; RP70; HPRP4; Prp4p; HPRP4P; SNRNP60
NCBI Protein Information
U4/U6 small nuclear ribonucleoprotein Prp4
UniProt Protein Name
U4/U6 small nuclear ribonucleoprotein Prp4
UniProt Gene Name
PRPF4
UniProt Synonym Gene Names
PRP4; hPrp4
UniProt Entry Name
PRP4_HUMAN

NCBI Description

The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

Uniprot Description

PRPF4: Involved in pre-mRNA splicing. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Spliceosome; RNA splicing; RNA processing

Chromosomal Location of Human Ortholog: 9q31-q33

Cellular Component: Cajal body; nuclear speck; nucleoplasm; nucleus; spliceosome; U4/U6 x U5 tri-snRNP complex

Molecular Function: protein binding; U4 snRNA binding; U6 snRNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing

Disease: Retinitis Pigmentosa 70

Research Articles on PRPF4

Similar Products

Product Notes

The PRPF4 prpf4 (Catalog #AAA7045737) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRPF4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRPF4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the PRPF4 prpf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRPF4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.