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Testing Data (Western Blot analysis 1)HepG2, 2)293T, 3) Mouse Brain Tissue, 4)Rat Brain Tissue with Lamin B1 Mouse Monoclonal Antibody (7C11) diluted at 1:5,000)

alpha-tubulin Monoclonal Antibody | anti-LMNB1 antibody

alpha-tubulin Mouse Monoclonal Antibody

Gene Names
LMNB1; LMN; ADLD; LMN2; LMNB
Reactivity
Human, Rat, Mouse
Applications
Western Blot, Immunoprecipitation
Synonyms
alpha-tubulin; Monoclonal Antibody; alpha-tubulin Mouse Monoclonal Antibody; anti-LMNB1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Rat, Mouse
Clonality
Monoclonal
Clone Number
7C11
Specificity
The alpha-tubulin antibody can detects endogenousalpha-tubulin protein
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
586
Applicable Applications for anti-LMNB1 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
WB: 1:2,000-5,000
IP:1:200
Preparation and Storage
Store at-20 degree C for 1 year. Do not aliquot the antibody.

Testing Data

(Western Blot analysis 1)HepG2, 2)293T, 3) Mouse Brain Tissue, 4)Rat Brain Tissue with Lamin B1 Mouse Monoclonal Antibody (7C11) diluted at 1:5,000)

Testing Data (Western Blot analysis 1)HepG2, 2)293T, 3) Mouse Brain Tissue, 4)Rat Brain Tissue with Lamin B1 Mouse Monoclonal Antibody (7C11) diluted at 1:5,000)
Related Product Information for anti-LMNB1 antibody
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
66,408 Da
NCBI Official Full Name
lamin B1
NCBI Official Synonym Full Names
lamin B1
NCBI Official Symbol
LMNB1
NCBI Official Synonym Symbols
LMN; ADLD; LMN2; LMNB
NCBI Protein Information
lamin-B1
UniProt Protein Name
Lamin-B1
UniProt Gene Name
LMNB1
UniProt Synonym Gene Names
LMN2; LMNB

NCBI Description

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Uniprot Description

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Research Articles on LMNB1

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Product Notes

The LMNB1 lmnb1 (Catalog #AAA8502791) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The alpha-tubulin Mouse Monoclonal Antibody reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's alpha-tubulin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB: 1:2,000-5,000 IP:1:200. Researchers should empirically determine the suitability of the LMNB1 lmnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "alpha-tubulin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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