Immunohistochemistry - Paraffin (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Mouse anti-Human ALDH1L1 Monoclonal Antibody | anti-ALDH1L1 antibody
Anti-ALDH1L1 Antibody (clone 7G8) IHC-plus
IF (1:100)
IHC-P (10 ug/ml)
WB (1:2000)
Immunohistochemistry - Paraffin (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry - Paraffin (IHC)
(Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunofluorescence (IF)
(Anti-ALDH1L1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ALDH1L1.)
Immunofluorescence (IF)
(Anti-ALDH1L1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ALDH1L1.)
Western Blot (WB)
(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALDH1L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALDH1L1.)
Western Blot (WB)
(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALDH1L1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALDH1L1.)
Flow Cytometry (FC/FACS)
(HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ALDH1L1 antibody, and then analyzed by flow cytometry.)
Flow Cytometry (FC/FACS)
(HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ALDH1L1 antibody, and then analyzed by flow cytometry.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Uniprot Description
ALDH1L1: 2 isoforms of the human protein are produced by alternative splicing
Protein type: EC 1.5.1.6; Oxidoreductase; Cofactor and Vitamin Metabolism - one carbon pool by folate
Chromosomal Location of Human Ortholog: 3q21.3
Cellular Component: cytoplasm; mitochondrion
Molecular Function: 4-trimethylammoniobutyraldehyde dehydrogenase activity; aminobutyraldehyde dehydrogenase activity; catalytic activity; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity; methyltransferase activity
Biological Process: 10-formyltetrahydrofolate catabolic process; biosynthetic process; methylation; one-carbon compound metabolic process
Research Articles on ALDH1L1
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Product Notes
The ALDH1L1 aldh1l1 (Catalog #AAA249488) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-ALDH1L1 Antibody (clone 7G8) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH1L1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS). Flow Cytometry (1:100) IF (1:100) IHC-P (10 ug/ml) WB (1:2000). Researchers should empirically determine the suitability of the ALDH1L1 aldh1l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH1L1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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