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Western Blot (WB) (Western blot analysis of anti-ALDH1L1 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). ALDH1L1(arrow) was detected using the purified Pab.)

Rabbit anti-Human, Mouse ALDH1L1 Polyclonal Antibody | anti-ALDH1L1 antibody

ALDH1L1, CT (Aldehyde Dehydrogenase Family 1 Member L1, 10-formyltetrahydrofolate Dehydrogenase, 10-FTHFDH, FTHFD)

Gene Names
ALDH1L1; FDH; FTHFD; 10-fTHF; DKFZp781N0997
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified
Purified by ammonium sulfate precipitation.
Synonyms
ALDH1L1; Polyclonal Antibody; CT (Aldehyde Dehydrogenase Family 1 Member L1; 10-formyltetrahydrofolate Dehydrogenase; 10-FTHFDH; FTHFD); Anti -ALDH1L1; anti-ALDH1L1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ALDH1L1. Species Crossreactivity: mouse
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Applicable Applications for anti-ALDH1L1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Immunogen
Synthetic peptide corresponding to a region between aa724-754 from the C-terminal region of human ALDH1L1, conjugated to KLH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-ALDH1L1 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). ALDH1L1(arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of anti-ALDH1L1 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). ALDH1L1(arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH1L1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH1L1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Related Product Information for anti-ALDH1L1 antibody
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Product Categories/Family for anti-ALDH1L1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
98,829 Da
NCBI Official Full Name
aldehyde dehydrogenase family 1 member L1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member L1
NCBI Official Symbol
ALDH1L1
NCBI Official Synonym Symbols
FDH; FTHFD; 10-fTHF; DKFZp781N0997
NCBI Protein Information
aldehyde dehydrogenase family 1 member L1; 10-FTHFDH; OTTHUMP00000155221; OTTHUMP00000214696; OTTHUMP00000214700; OTTHUMP00000222724; formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase; cytosolic 10-formyltetrahydrofolate dehydrogenase
UniProt Protein Name
Aldehyde dehydrogenase family 1 member L1
UniProt Gene Name
ALDH1L1
UniProt Synonym Gene Names
FTHFD
UniProt Entry Name
AL1L1_HUMAN

NCBI Description

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning. [provided by RefSeq]

Uniprot Description

ALDH1L1: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Oxidoreductase; Cofactor and Vitamin Metabolism - one carbon pool by folate; EC 1.5.1.6

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: mitochondrion

Molecular Function: methyltransferase activity; aldehyde dehydrogenase (NAD) activity; hydroxymethyl-, formyl- and related transferase activity; formyltetrahydrofolate dehydrogenase activity; catalytic activity

Biological Process: methylation; biosynthetic process; one-carbon compound metabolic process; 10-formyltetrahydrofolate catabolic process

Research Articles on ALDH1L1

Similar Products

Product Notes

The ALDH1L1 aldh1l1 (Catalog #AAA625744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALDH1L1, CT (Aldehyde Dehydrogenase Family 1 Member L1, 10-formyltetrahydrofolate Dehydrogenase, 10-FTHFDH, FTHFD) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH1L1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the ALDH1L1 aldh1l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH1L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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