Immunohistochemistry (IHC)
(AEG1 [IHC507] on Stomach Cancer)
Mouse anti-Human Actin Monoclonal Antibody
Actin, Smooth Muscle
Reactivity
Human
Synonyms
Actin; Monoclonal Antibody; Smooth Muscle; AEG1; anti-Actin antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Application Notes
The recommended working dilution range is 1:100-1:200
Positive Control
Glioblastoma
Immunohistochemistry (IHC)
(AEG1 [IHC507] on Stomach Cancer)
Immunohistochemistry (IHC)
(AEG1 [IHC507] on Stomach Cancer)
Related Product Information for anti-Actin antibody
Astrocyte Elevated Gene-1 protein (AEG1) is an oncoprotein involved in many hallmarks of aggressive cancer progression such as apoptosis evasion, cell movement, transformation, invasion, angiogenesis, metastasis and drug resistance. AEG1 plays an important role in anchorage-independent growth of cancer cells, which allow for tumor cell expansions. It is also implicated in diverse physiological and pathological processes, such as development, inflammation, neurodegeneration, migraine and Huntington's disease. AEG1 is found to be overexpressed in melanoma, malignant glioma, and breast cancer, and is associated with poor clinical outcomes in hepatocellular carcinoma. The protein is a potential therapeutic target for reducing metastasis and enhancing chemotherapy.
References
1. Brown DM, et al. Cancer Cell. 2004; 5:365-74.
2. Yoo BK, et al. Pharmacol Ther. 2011; 130:1-8.
3. Yoo BK, et al. J Clin Invest. 2009; 119:465-77.
4. Hu G, et al. Cancer Cell. 2009; 15:9-20.
2. Yoo BK, et al. Pharmacol Ther. 2011; 130:1-8.
3. Yoo BK, et al. J Clin Invest. 2009; 119:465-77.
4. Hu G, et al. Cancer Cell. 2009; 15:9-20.
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Product Notes
The Actin (Catalog #AAA344036) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Actin, Smooth Muscle reacts with Human and may cross-react with other species as described in the data sheet. The recommended working dilution range is 1:100-1:200. Researchers should empirically determine the suitability of the Actin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Actin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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