Typical Testing Data/Standard Curve (for reference only)

Rat Neprilysin ELISA Kit | Mme elisa kit

Rat Neprilysin ELISA Kit

Gene Names

Mme; Nep; SFE; CD10

Reactivity

Rat

Synonyms

Neprilysin; Rat Neprilysin ELISA Kit; Atriopeptidase; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; Mme; 3.4.24.11; CD10; Mme elisa kit

Ordering
Cat. Num. AAA2883169 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Rat

Sequence Length

750

Assay Type

Sandwich

Detection Range

0.156-10 ng/mL

Sensitivity

0.081 ng/mL

Intra-Assay CV

<=4.5%

Inter-Assay CV

<=9.6%

Recovery

99%

Preparation and Storage

For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #

6981210

NCBI GeneID

24590

NCBI Accession #

NP_036740.1

NCBI GenBank Nucleotide #

NM_012608.2

UniProt Accession #

P07861

Molecular Weight

85,795 Da

NCBI Official Full Name

neprilysin

NCBI Official Synonym Full Names

membrane metallo-endopeptidase

NCBI Official Symbol

Mme

NCBI Official Synonym Symbols

Nep; SFE; CD10

NCBI Protein Information

neprilysin

UniProt Protein Name

Neprilysin

Protein Family

Neprilysin

UniProt Gene Name

Mme

UniProt Synonym Gene Names

NEP; Neutral endopeptidase; SFE

UniProt Entry Name

NEP_RAT

NCBI Description

zinc-containing metallo-enzyme; involved in degradation of cardiac peptides [RGD, Feb 2006]

Uniprot Description

CD10: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers. Inhibited in a dose dependent manner by opiorphin. Belongs to the peptidase M13 family.

Protein type: Membrane protein, integral; Protease; EC 3.4.24.11

Cellular Component: axon; brush border; cytoplasm; dendrite; focal adhesion; integral to membrane; membrane; plasma membrane; synapse; synaptic vesicle

Molecular Function: endopeptidase activity; exopeptidase activity; metalloendopeptidase activity; peptidase activity; peptide binding; zinc ion binding

Biological Process: beta-amyloid metabolic process; creatinine metabolic process; kidney development; peptide metabolic process; proteolysis; sensory perception of pain

Research Articles on Mme

1. the increased expression of NPR-C (r=-0.943 and -0.837 for mRNA and protein respectively, p<0.05) and NEP (r=-0.687 and -0.823 for mRNA and protein respectively, p<0.05) were accompanied by a signi fi cant decline in CNP.

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Product Notes

The Rat Mme mme (Catalog #AAA2883169) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883169 ELISA Kit recognizes Rat Mme. It is sometimes possible for the material contained within the vial of "Neprilysin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Rat Neprilysin ELISA Kit | Mme elisa kit