Testing Data
(Image: Staining of mouse nob rescue retinal sections.)
anti-Mouse, Rat mGluR5b Antibody | anti-mGluR6 antibody
mGluR5b, Affinity Purified Antibody, Rabbit
Gene Names
GRM5; mGlu5; GPRC1E; MGLUR5; PPP1R86
Reactivity
Mouse, Rat
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Synonyms
mGluR5b; Affinity Purified Antibody; Rabbit; anti-mGluR6 antibody
Reactivity
Mouse, Rat
Form/Format
Affinity Purified - Liquid
Sequence Length
1212
Applicable Applications for anti-mGluR6 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB)
Type Info
Rabbit IgG
Immunogen
AAPPQNENAEDAK
Testing Data
(Image: Staining of mouse nob rescue retinal sections.)
Testing Data
(Image: Staining of mouse nob rescue retinal sections.)
Testing Data
(Image: mGluR6 staining of GluR6 in trapezoid body in mouse brain using anti-rabbit Cy3 conjugated secondary antibodies (red color). DAPI was used to counterstain cell nuclei. Dilution 1:30. Tissue was mounted to slide using i-BRITE Plus anti fade media.)
Testing Data
(Image: mGluR6 staining of GluR6 in trapezoid body in mouse brain using anti-rabbit Cy3 conjugated secondary antibodies (red color). DAPI was used to counterstain cell nuclei. Dilution 1:30. Tissue was mounted to slide using i-BRITE Plus anti fade media.)
Related Product Information for anti-mGluR6 antibody
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
Product Categories/Family for anti-mGluR6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
105,432 Da
NCBI Official Full Name
Metabotropic Glutamate Receptor Subtype 5b
NCBI Official Synonym Full Names
glutamate metabotropic receptor 5
NCBI Official Symbol
GRM5
NCBI Official Synonym Symbols
mGlu5; GPRC1E; MGLUR5; PPP1R86
NCBI Protein Information
metabotropic glutamate receptor 5
UniProt Protein Name
Metabotropic glutamate receptor 5
UniProt Gene Name
GRM5
UniProt Synonym Gene Names
GPRC1E; MGLUR5; mGluR5
UniProt Entry Name
GRM5_HUMAN
Uniprot Description
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
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Product Notes
The mGluR6 grm5 (Catalog #AAA555557) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The mGluR5b, Affinity Purified Antibody, Rabbit reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's mGluR5b can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the mGluR6 grm5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "mGluR5b, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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