SDS-PAGE
rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1) Recombinant Protein | FIB1 recombinant protein
Recombinant Arabidopsis thaliana rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1)
Gene Names
FIB1; ATFBR1; ATFIB1; FBR1; FIB1; fibrillarin 1; FIBRILLARIN 1; K24M7.22; K24M7_22; SKIP7; SKP1/ASK1-INTERACTING PROTEIN
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1); Recombinant Arabidopsis thaliana rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1); rRNA 2'-O-methyltransferase fibrillarin 1; EC=2.1.1.-; SKP1-interacting partner 7; FIB1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-308aa; Full Length
Sequence
MRPPVTGGRGGGGFRGGRDGGGRGFGGGRSFGGGRSGDRGRSGPRGRGRGAPRGRGGPPRGGMKGGSKVIVEPHRHAGVFIAKGKEDALVTKNLVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRSKLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASFFLKTGGHFVISIKANCIDSTVAAEAVFQSEVKKLQQEQFKPAEQVTLEPFERDHACVVGGYRMPKKQKTPAS
Sequence Length
308
Species
Arabidopsis thaliana (Mouse-ear cress)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
SDS-PAGE
SDS-PAGE
Related Product Information for FIB1 recombinant protein
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48.8 kDa
NCBI Official Full Name
probable mediator of RNA polymerase II transcription subunit 36b
NCBI Official Symbol
FIB1
NCBI Official Synonym Symbols
ATFBR1; ATFIB1; FBR1; FIB1; fibrillarin 1; FIBRILLARIN 1; K24M7.22; K24M7_22; SKIP7; SKP1/ASK1-INTERACTING PROTEIN
NCBI Protein Information
probable mediator of RNA polymerase II transcription subunit 36b
UniProt Protein Name
Probable mediator of RNA polymerase II transcription subunit 36b
UniProt Gene Name
MED36B
UniProt Synonym Gene Names
FBR1; FIB1; MED36_2; SKIP7
UniProt Entry Name
MD36B_ARATH
Uniprot Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors ().
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Product Notes
The FIB1 med36b (Catalog #AAA1300267) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-308aa; Full Length. The amino acid sequence is listed below: MRPPVTGGRG GGGFRGGRDG GGRGFGGGRS FGGGRSGDRG RSGPRGRGRG APRGRGGPPR GGMKGGSKVI VEPHRHAGVF IAKGKEDALV TKNLVPGEAV YNEKRISVQN EDGTKVEYRV WNPFRSKLAA AILGGVDNIW IKPGAKVLYL GAASGTTVSH VSDLVGPEGC VYAVEFSHRS GRDLVNMAKK RTNVIPIIED ARHPAKYRML VGMVDVIFSD VAQPDQARIL ALNASFFLKT GGHFVISIKA NCIDSTVAAE AVFQSEVKKL QQEQFKPAEQ VTLEPFERDH ACVVGGYRMP KKQKTPAS. It is sometimes possible for the material contained within the vial of "rRNA 2'-O-methyltransferase fibrillarin 1 (FIB1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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