SDS-PAGE
LRRTM4 recombinant protein
Recombinant Human LRRTM4 Protein (His tag)
Purity
> 97 % as determined by SDS-PAGE
Synonyms
LRRTM4; Recombinant Human LRRTM4 Protein (His tag); UNQ3075/PRO9907; FLJ12568; MGC120633; MGC120636; LRRTM4 recombinant protein
Host
Human Cells
Purity/Purification
> 97 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
590
Application Notes
The recombinant human LRRTM4 consists of 405 amino acids and predictes a molecular mass of 46.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh LRRTM4 is approximately 65 kDa due to glycosylation.
Predicted N Terminal
Gln 31
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for LRRTM4 recombinant protein
Background: Leucine-rich repeat transmembrane neuronal protein 4, also known as LRRTM4, is a single-pass type I membrane protein which belongs to the LRRTM family. LRRTM4 is expressed in the limb mesenchyme, neural tube, caudal mesoderm and in three distinct regions of the head. LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system. Leucine-rich repeat containing proteins are involved in protein-protein interactions and they regulate numerous cellular events during nervous system development and disease. Human and mouse LRRTMs are highly conserved, and orthologous genes exist in other vertebrates but not in invertebrates. LRRTM mRNAs are predominantly expressed in the nervous system and that each LRRTM possesses a specific, partially nonoverlapping expression pattern. The structure and expression profile of LRRTM mRNAs suggest that they may have a role in the development and maintenance of the vertebrate nervous system. All LRRTMs, except LRRTM4, are located in the introns of different alpha-catenin genes, suggesting coevolution of these two gene families.
Description: A DNA sequence encoding the human LRRTM4 extracellular domain (NP_001128217.1) (Met 1-Lys 424) was expressed, fused with a polyhistidine tag at the C-terminus.
Description: A DNA sequence encoding the human LRRTM4 extracellular domain (NP_001128217.1) (Met 1-Lys 424) was expressed, fused with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,126 Da
NCBI Official Full Name
leucine-rich repeat transmembrane neuronal protein 4 isoform a
NCBI Official Synonym Full Names
leucine rich repeat transmembrane neuronal 4
NCBI Official Symbol
LRRTM4
NCBI Protein Information
leucine-rich repeat transmembrane neuronal protein 4
UniProt Protein Name
Leucine-rich repeat transmembrane neuronal protein 4
Protein Family
UniProt Gene Name
LRRTM4
Uniprot Description
LRRTM4: May play a role in the development and maintenance of the vertebrate nervous system. Belongs to the LRRTM family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell development/differentiation; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p12
Cellular Component: cytoplasm
Molecular Function: protein kinase inhibitor activity
Biological Process: cytokine and chemokine mediated signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity
Research Articles on LRRTM4
Similar Products
Product Notes
The LRRTM4 lrrtm4 (Catalog #AAA2545796) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant human LRRTM4 consists of 405 amino acids and predictes a molecular mass of 46.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh LRRTM4 is approximately 65 kDa due to glycosylation. Researchers should empirically determine the suitability of the LRRTM4 lrrtm4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRTM4, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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