Lysocardiolipin acyltransferase 1 (LCLAT1) Recombinant Protein | LCLAT1 recombinant protein
Recombinant Human Lysocardiolipin acyltransferase 1 (LCLAT1)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
AGPAT8: Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - glycerophospholipid; Amino Acid Metabolism - phenylalanine; Endoplasmic reticulum; Membrane protein, multi-pass; Lipid Metabolism - ether lipid; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - tyrosine; Membrane protein, integral; Transferase; Lipid Metabolism - glycerolipid; EC 2.3.1.51
Chromosomal Location of Human Ortholog: 2p23.1
Cellular Component: endoplasmic reticulum membrane; integral to membrane; membrane
Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; O-acyltransferase activity; protein binding
Biological Process: CDP-diacylglycerol biosynthetic process; multicellular organismal development; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process
Research Articles on LCLAT1
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Product Notes
The LCLAT1 lclat1 (Catalog #AAA7018253) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-414aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the LCLAT1 lclat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MHSRGREIVV LLNPWSINEA VSSYCTYFIK QDSKSFGIMV SWKGIYFILT LFWGSFFGSI FMLSPFLPLM FVNPSWYRWI NNRLVATWLT LPVALLETMF GVKVIITGDA FVPGERSVII MNHRTRMDWM FLWNCLMRYS YLRLEKICLK ASLKGVPGFG WAMQAAAYIF IHRKWKDDKS HFEDMIDYFC DIHEPLQLLI FPEGTDLTEN SKSRSNAFAE KNGLQKYEYV LHPRTTGFTF VVDRLREGKN LDAVHDITVA YPHNIPQSEK HLLQGDFPRE IHFHVHRYPI DTLPTSKEDL QLWCHKRWEE KEERLRSFYQ GEKNFYFTGQ SVIPPCKSEL RVLVVKLLSI LYWTLFSPAM CLLIYLYSLV KWYFIITIVI FVLQERIFGG LEIIELACYR LLHKQPHLNS KKNE. It is sometimes possible for the material contained within the vial of "Lysocardiolipin acyltransferase 1 (LCLAT1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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