Rabbit anti-Human PIP5KI gamma Polyclonal Antibody | anti-Pip5k1c antibody

PIP5KI gamma, NT (Phosphatidylinositol-4-phosphate 5-kinase, Type I, gamma, PtdIns(4)P-5-kinase 1 gamma, Phosphatidylinositol-4-phosphate 5-kinase Type I gamma, PIP5KIgamma, PIP5K1C, KIAA0589)

Cat. Num. AAA630965

• Gene Names: Pip5k1c; AI115456; AI835305; Pip5kIgamma
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: PIP5KI gamma; Polyclonal Antibody; NT (Phosphatidylinositol-4-phosphate 5-kinase; Type I; gamma; PtdIns(4)P-5-kinase 1 gamma; Phosphatidylinositol-4-phosphate 5-kinase Type I gamma; PIP5KIgamma; PIP5K1C; KIAA0589); Anti -PIP5KI gamma; anti-Pip5k1c antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PIP5K1G.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.09% sodium azide.

• Applicable Applications for anti-Pip5k1c antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot, and Immunohistochemistry.; Dilution: ELISA: 1:1,000; Western Blot: 1:100-1:500; Immunohistochemistry: 1:50-1:100
• Immunogen: Synthetic peptide selected from the N-terminal region of human PIP5K1G (KLH).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(The anti-PIP5K1G Pab is used in Western blot to detect PIP5K1G in 293 cell lysate.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)

Related Product Information for anti-Pip5k1c antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Product Categories/Family for anti-Pip5k1c antibody

Antibodies; Abs to Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 78099089
• NCBI GeneID: 18717
• UniProt Accession #: O70161; Q505A1; Q80TW9; Q8VCU5
• Molecular Weight: 72,408 Da
• NCBI Official Full Name: Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
• NCBI Official Synonym Full Names: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
• NCBI Official Symbol: Pip5k1c
• NCBI Official Synonym Symbols: AI115456; AI835305; Pip5kIgamma
• NCBI Protein Information: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; ptdIns(4)P-5-kinase 1 gamma; phosphatidylinositol 4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
• UniProt Protein Name: Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
• Protein Family: Phosphatidylinositol 4-phosphate 5-kinase
• UniProt Gene Name: Pip5k1c
• UniProt Synonym Gene Names: Kiaa0589; PIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; PIP5KIgamma
• UniProt Entry Name: PI51C_MOUSE

Uniprot Description

PIP5K1C: a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus.

Protein type: Motility/polarity/chemotaxis; Kinase, lipid; Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.68

Cellular Component: cell projection; membrane; cell; cytoplasm; plasma membrane; cell junction

Molecular Function: transferase activity; protein binding; phosphatidylinositol phosphate kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; nucleotide binding; kinase activity; ATP binding

Biological Process: exocytosis; axonogenesis; cytoskeletal anchoring; phosphoinositide phosphorylation; endocytosis; phosphatidylinositol metabolic process; cell adhesion; chemotaxis; phosphorylation; phagocytosis