SDS-Page
NKG2-D type II Integral Membrane Protein/NKG2D/CD314 Recombinant Protein | NKG2-D recombinant protein
Recombinant Mouse NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His)
Gene Names
Klrk1; Nkg2d; NKG2-D; D6H12S2489E
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
NKG2-D type II Integral Membrane Protein/NKG2D/CD314; Recombinant Mouse NKG2-D type II Integral Membrane Protein/NKG2D/CD314 (N-6His); CD314; KLRK1; CD314 antigen; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K; member 1; KLR; NK cell receptor D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKG2D; NKG2-D recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2um filtered solution of PBS, pH7.4.
Sequence
Phe94-Val232
Species
Mouse
Tag
N-6His
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Recombinant Mouse NKG2-D type II Integral Membrane Protein is produced by our Mammalian expression system and the target gene encoding Phe94-Val232 is expressed with a 6His tag at the N-terminus.
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
This product is provided as lyophilized powder which is shipped with ice packs.
This product is provided as lyophilized powder which is shipped with ice packs.
SDS-Page
SDS-Page
Related Product Information for NKG2-D recombinant protein
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural killer (NK) cells, CD8+ alpha-beta and gamma-delta T-cells. As an activating and costimulatory receptor, it involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. It provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. It stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. NKG2D participates in NK cell-mediated bone marrow graft rejection and survival of NK cells. It Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,710 Da
NCBI Official Full Name
NKG2-D type II integral membrane protein isoform b
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily K, member 1
NCBI Official Symbol
Klrk1
NCBI Official Synonym Symbols
Nkg2d; NKG2-D; D6H12S2489E
NCBI Protein Information
NKG2-D type II integral membrane protein; NK cell receptor D; natural killer cell group 2D; NKG2-D-activating NK receptor
UniProt Protein Name
NKG2-D type II integral membrane protein
UniProt Gene Name
Klrk1
UniProt Synonym Gene Names
Nkg2d
UniProt Entry Name
NKG2D_MOUSE
Similar Products
Product Notes
The NKG2-D klrk1 (Catalog #AAA2569338) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Phe94-Val2 32. It is sometimes possible for the material contained within the vial of "NKG2-D type II Integral Membrane Protein/NKG2D/CD314, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
